London Daily

Focus on the big picture.
Saturday, Jul 05, 2025

Pfizer, BioNTech Say Covid Vaccine Effective Against South African Variant

Pfizer, BioNTech Say Covid Vaccine Effective Against South African Variant

No cases of the disease were observed in South Africa during the phase-three trial study among participants who had received their second dose, the companies said in a statement.
Pfizer and BioNTech said Thursday their Covid-19 vaccine was highly effective against the South African variant in the latest phase of ongoing clinical trials.

No cases of the disease were observed in South Africa during the phase-three trial study among participants who had received their second dose, the companies said in a statement.

Several coronavirus variants with the potential to be more transmissible have caused global concern over whether existing vaccines will still protect the world from a virus that is constantly mutating.

"In South Africa, where the B.1.351 lineage is prevalent and 800 participants were enrolled, nine cases of Covid-19 were observed, all in the placebo group," the companies said.

The nine strains were sequenced and six of them were confirmed to be of B.1.351 lineage, they said.

"The high vaccine efficacy observed through up to six months following a second dose and against the variant prevalent in South Africa provides further confidence in our vaccine's overall effectiveness," said Albert Bourla, chief executive of Pfizer.

Overall, the vaccine was 91.3 percent effective against Covid-19 in the analysis of 46,307 trial participants across several countries.

From the 927 confirmed symptomatic cases of Covid-19 in the trial, 850 cases were in the placebo group and 77 cases were in the vaccinated group.

The vaccine was 100 percent effective in preventing severe disease as defined by the US Centers for Disease Control and Prevention, and 95.3 percent effective in preventing severe disease as defined by the US Food and Drug Administration.

Pfizer and BioNTech had said in January that "small differences" detected in tests comparing the original virus and the recent versions "are unlikely to lead to a significant reduction in the effectiveness of the vaccine".

The companies said Thursday the new data "support previous results from immunogenicity studies demonstrating that (the vaccine) induced a robust neutralising antibody response to the B1.351 (South African) variant, and although lower than to the wild-type strain, it does not appear to affect the high observed efficacy against this variant".

Global deaths from Covid-19 have topped 2.8 million since the pandemic began a year ago, with vaccines seen as the only real chance of returning to some form of normality.
Newsletter

Related Articles

0:00
0:00
Close
Elon Musk Founds a Party Following a Poll on X: "You Wanted It – You Got It!"
London Stock Exchange Faces Historic Low in Initial Public Offerings
A new online platform has emerged in the United Kingdom, specifically targeting Muslim men seeking virgin brides
Trump Celebrates Independence Day with B-2 Flyover and Signs Controversial Legislation
Boris Johnson Urges Conservatives to Ignore Farage
SNP Ordered to Update Single-Sex Space Guidance Within Days
Starmer Set to Reject Calls for Wealth Taxes
Stolen Century-Old Rolls-Royce Recovered After Hotel Theft
Macron Presses Starmer to Recognise Palestinian State
Labour Delayed Palestine Action Ban Over Riot Concerns
Swinney’s Tax Comments ‘Offensive to Scots’, Say Tories
High Street Retailers to Enforce Bans on Serial Shoplifters
Music Banned by Henry VIII to Be Performed After 500 Years
Steve Coogan Says Working Class Is Being ‘Ethnically Cleansed’
Home Office Admits Uncertainty Over Visa Overstayer Numbers
JD Vance Questions Mandelson Over Reform Party’s Rising Popularity
Macron to Receive Windsor Carriage Ride in Royal Gesture
Labour Accused of ‘Hammering’ Scots During First Year in Power
BBC Head of Music Stood Down Amid Bob Vylan Controversy
Corbyn Eyes Hard-Left Challenge to Starmer’s Leadership
London Tube Trains Suspended After Major Fire Erupts Nearby
Richard Kemp: I Felt Safer in Israel Under Attack Than in the UK
Cyclist Says Police Cited Human Rights Act for Riding No-Handed
China’s Central Bank Consults European Peers on Low-Rate Strategies
AI Raises Alarms Over Long-Term Job Security
Saudi Arabia Maintains Ties with Iran Despite Israel Conflict
Musk Battles to Protect Tesla Amid Trump Policy Threats
Air France-KLM Acquires Majority Stake in Scandinavian Airlines
UK Educators Sound Alarm on Declining Child Literacy
Shein Fined €40 Million in France Over Misleading Discounts
Brazil’s Lula Visits Kirchner During Argentina House Arrest
Trump Scores Legislative Win as House Passes Tax Reform Bill
Keir Starmer Faces Criticism After Rocky First Year in Power
DJI Launches Heavy-Duty Coaxial Quadcopter with 80 kg Lift Capacity
U.S. Senate Approves Major Legislation Dubbed the 'Big Beautiful Bill'
Largest Healthcare Fraud Takedown in U.S. History Announced by DOJ
Poland Implements Border Checks Amid Growing Migration Tensions
Political Dispute Escalates Between Trump and Musk
Emirates Airline Expands Market Share with New $20 Million Campaign
Amazon Reaches Milestone with Deployment of One Millionth Robot
US Senate Votes to Remove AI Regulation Moratorium from Domestic Policy Bill
Yulia Putintseva Calls for Spectator Ejection at Wimbledon Over Safety Concerns
Jury Deliberations in Diddy Trial Yield Partial Verdict in Serious Criminal Charges
House Oversight Committee Subpoenas Former Jill Biden Aide Amid Investigation into Alleged Concealment of President Biden's Cognitive Health
King Charles Plans Significant Role for Prince Harry in Coronation
Two Chinese Nationals Arrested for Espionage Activities Against U.S. Navy
Amazon Reaches Major Automation Milestone with Over One Million Robots
Extreme Heat Wave Sweeps Across Europe, Hitting Record Temperatures
Meta Announces Formation of Ambitious AI Unit, Meta Superintelligence Labs
Robots Compete in Football Tournament in China Amid Injuries
×