London Daily

Focus on the big picture.
Sunday, Nov 16, 2025

Omicron: How do you detect it?

Omicron: How do you detect it?

The first cases of the new Omicron variant of coronavirus have now been detected in the UK, after it was highlighted by scientists in South Africa as a potentially worrying new strain.
What tests are used to detect Omicron?


Swabs from PCR tests, which are sent to a lab for analysis, detect whether people are infected with coronavirus or not.

Depending on which lab the swabs are sent to, some can also help identify particular variants, such as Delta or Omicron.

Between a third and a half of UK labs - but not all - have the required technology to do this.

PCR tests are the ones you can order from the government website if you have symptoms, or order from a private company if you need one for travel purposes. There are many different makes.

How do we know that Omicron is in the UK?


The swabs from PCR tests that have given a positive result for what looks like Omicron have been sent to a lab for a full genetic analysis, using a technique known as genomic sequencing.

This has confirmed that some people have indeed been infected with the latest variant.

This laboratory analysis of the genetic material of the virus is key to detecting variants and finding out how they act.

It is likely there are many more cases of the variant already in the UK, but as yet undetected, because it can take a couple of weeks for this process to be completed.

The dominant variant of coronavirus is still Delta, which is responsible for around 40,000 new cases every day in the UK.

Do lateral flow tests detect Omicron?


Rapid or lateral flow tests, which can be used at home, can't tell you which variant you're infected with - but they are still thought to be able to tell you if you're negative or positive, even with Omicron.

What's the difference between Omicron and other variants?


The Omicron variant has lots of different mutations that haven't been seen before, and many that have.

A large number of them are on the spike protein of the virus, which is the target of most vaccines, and that's the main concern.

In standard tests, Omicron has what's known as an "S-gene dropout" which makes tracking positive cases which resemble the variant pretty easy.

But not all "S-gene dropouts" will necessarily be omicron - full genomic sequencing is needed to be sure.


What role does genomic sequencing play?


Analysing the genetic make-up of the virus is a crucial part of working how which variant is involved.

Up to 20% of the swabs from positive test results in the UK each week, or around 60,000 cases, are sent for genomic sequencing.

By looking closely at the genetic material provided, scientists can confirm whether someone is positive with Omicron or the already widely-circulating Delta.

This process only provides information about the swabs that are analysed - but using those results, scientists are able to estimate what proportion of new cases could be the new variant.

Scientists in the UK and South African are at the forefront of this technology, which is why most new variants have been detected in these countries. But that doesn't always mean they originated there.

What do we know about Omicron?


Very little is known about how the variant acts or how much of a threat it could be.

For example, it's not clear if it spreads more easily, if it makes people more unwell than other variants or if protection from vaccines will be less than previously thought.

But on paper it looks worrying and that's why governments are acting quickly, in case it's bad news.

Newsletter

Related Articles

0:00
0:00
Close
Nearly Half of Job Losses Under Labour Government Affect UK Youth
UK Chancellor Reeves Eyes High-Value Home Levy in Budget to Raise Tens of Billions
UK Urges Poland to Choose Swedish Submarines in Multi-Billion € Defence Bid
US Border Czar Tom Homan Declares UK No Longer a ‘Friend’ Amid Intelligence Rift
UK Announces Reversal of Income Tax Hike Plans Ahead of Budget
Starmer Faces Mounting Turmoil as Leaked Briefings Ignite Leadership Plot Rumours
UK Commentator Sami Hamdi Returns Home After US Visa Revocation and Detention
UK Eyes Denmark-Style Asylum Rules in Major Migration Shift
UK Signals Intelligence Freeze Amid US Maritime Drug-Strike Campaign
TikTok Awards UK & Ireland 2025 Celebrates Top Creators Including Max Klymenko as Creator of the Year
UK Growth Nearly Stalls at 0.1% in Q3 as Cyberattack Halts Car Production
Apple Denied Permission to Appeal UK App Store Ruling, Faces Over £1bn Liability
UK Chooses Wylfa for First Small Modular Reactors, Drawing Sharp U.S. Objection
Starmer Faces Growing Labour Backlash as Briefing Sparks Authority Crisis
Reform UK Withdraws from BBC Documentary Amid Legal Storm Over Trump Speech Edit
UK Prime Minister Attempts to Reassert Authority Amid Internal Labour Leadership Drama
UK Upholds Firm Rules on Stablecoins to Shield Financial System
Brussels Divided as UK-EU Reset Stalls Over Budget Access
Prince Harry’s Remembrance Day Essay Expresses Strong Regret at Leaving Britain
UK Unemployment Hits 5% as Wage Growth Slows, Paving Way for Bank of England Rate Cut
Starmer Warns of Resurgent Racism in UK Politics as He Vows Child-Poverty Reforms
UK Grocery Inflation Slows to 4.7% as Supermarkets Launch Pre-Christmas Promotions
UK Government Backs the BBC amid Editing Scandal and Trump Threat of Legal Action
UK Assessment Mis-Estimated Fallout From Palestine Action Ban, Records Reveal
UK Halts Intelligence Sharing with US Amid Lethal Boat-Strike Concerns
King Charles III Leads Britain in Remembrance Sunday Tribute to War Dead
UK Retail Sales Growth Slows as Households Hold Back Ahead of Black Friday and Budget
Shell Pulls Out of Two UK Floating Wind Projects Amid Renewables Retreat
Viagogo Hit With £15 Million Tax Bill After HMRC Transfer-Pricing Inquiry
Jaguar Land Rover Cyberattack Pinches UK GDP, Bank of England Says
UK and Germany Sound Alarm on Russian-Satellite Threat to Critical Infrastructure
Former Prince Andrew Faces U.S. Congressional Request for Testimony Amid Brexit of Royal Title
BBC Director-General Tim Davie and News CEO Deborah Turness Resign Amid Editing Controversy
Tom Cruise Arrives by Helicopter at UK Scientology Fundraiser Amid Local Protests
Prince Andrew and Sarah Ferguson Face Fresh UK Probes Amid Royal Fallout
Mothers Link Teen Suicides to AI Chatbots in Growing Legal Battle
UK Government to Mirror Denmark’s Tough Immigration Framework in Major Policy Shift
UK Government Turns to Denmark-Style Immigration Reforms to Overhaul Border Rules
UK Chancellor Warned Against Cutting Insulation Funding as Budget Looms
UK Tenant Complaints Hit Record Levels as Rental Sector Faces Mounting Pressure
Apple to Pay Google About One Billion Dollars Annually for Gemini AI to Power Next-Generation Siri
UK Signals Major Shift as Nuclear Arms Race Looms
BBC’s « Celebrity Traitors UK » Finale Breaks Records with 11.1 Million Viewers
UK Spy Case Collapse Highlights Implications for UK-Taiwan Strategic Alignment
On the Road to the Oscars? Meghan Markle to Star in a New Film
A Vote Worth a Trillion Dollars: Elon Musk’s Defining Day
AI Researchers Claim Human-Level General Intelligence Is Already Here
President Donald Trump Challenges Nigeria with Military Options Over Alleged Christian Killings
Nancy Pelosi Finally Announces She Will Not Seek Re-Election, Signalling End of Long Congressional Career
UK Pre-Budget Blues and Rate-Cut Concerns Pile Pressure on Pound
×