London Daily

Focus on the big picture.
Sunday, Nov 23, 2025

Covid vaccines cut risk of serious illness by 80% in over-80s

Covid vaccines cut risk of serious illness by 80% in over-80s

A single shot of either the Oxford-AstraZeneca or the Pfizer-BioNTech Covid jab reduces the chance of needing hospital treatment by more than 80%, an analysis in England shows.

The Public Health England data showed the effect kicked in three to four weeks after vaccination.

It was based on people aged over 80 who were the first to receive the jab.

Government scientists hailed the result, but stressed that two doses were needed for the best protection.

It comes after similar findings were published by Scottish health authorities last week, which they hailed as "spectacular".

Health Secretary Matt Hancock told a Downing Street briefing on Monday the latest vaccine results were "very strong".

He added: "They may also help to explain why the number of Covid admissions to intensive care units among people over 80 in the UK have dropped to single figures in the last couple of weeks."

Also speaking at the news conference, England's deputy chief medical officer - Prof Jonathan Van-Tam - said the data offered a glimpse of how the vaccine programme "is going to hopefully take us into a very different world in the next few months".

But he said it was "absolutely critical" that second doses "are still part of the course of immunisation against Covid-19 and no less important".

Prof Van-Tam stressed there was a "significant likelihood" that a second dose of a vaccine would "mature your immune response, possibly make it broader and almost certainly make it longer than it would otherwise be in relation to a first dose only."

More than 20 million people in the UK have had their first dose of a vaccine - over a third of the adult population.

Meanwhile, another 104 deaths within 28 days of a positive coronavirus have been reported in the UK, and a further 5,455 new cases, according to the latest figures.


The PHE data, which has not been peer reviewed, also suggested the Pfizer vaccine, which started being rolled out a month before the AstraZeneca vaccine, leads to an 83% reduction in deaths from Covid. This was based on people over the age of 80 who had died.

The data also showed vaccination cuts the risk of people over 70 developing any Covid symptoms by around 60%, three weeks after an initial dose.

Prof Van-Tam said the decision to give the AstraZeneca vaccine to older people was "clearly vindicated".

Some European nations have refused to give it to the over 65s because data from the trials was mainly on its effect among younger adults.

Prof Van-Tam said the judgement made by the UK authorities was that it was simply "not plausible" the vaccine would only work on younger adults.

He said other countries would doubtless be "very interested" in the data coming out of the UK.

Dr Mary Ramsay, Public Health England's head of immunisation, said there was growing evidence that the vaccines were working to reduce infections and save lives.

"While there remains much more data to follow, this is encouraging and we are increasingly confident that vaccines are making a real difference," she said.

However, more evidence is needed to know how well the vaccines protect against the Brazil variant that has recently been identified in the UK.

This variant has a mutation - E484 - that could reduce some of the effectiveness of the vaccines.

It was announced on Sunday that six new variant cases - three in England and three in Scotland - had been found through testing.

Health officials have been able to contact all but one of these people. The whereabouts of the remaining individual is unknown as they did not complete their test registration card.

It has prompted an appeal for anyone without a result from a test on 12 or 13 February to come forward immediately by calling 119.

The health secretary has denied that delays in imposing quarantine hotel measures on travellers to the UK put lives at risk, as officials continue to seek the individual.

Mr Hancock said there was "no evidence" the infected person had not followed home quarantine rules.

Earlier, Prime Minister Boris Johnson said the UK has "one of the toughest border regimes anywhere in the world for stopping people coming in to this country who may have variants of concern".

Newsletter

Related Articles

0:00
0:00
Close
Johnson Blasts ‘Incoherent’ Covid Inquiry Findings Amid Report’s Harsh Critique of His Government
Lord Rothermere Secures £500 Million Deal to Acquire Telegraph Titles
Maduro Tightens Security Measures as U.S. Strike Threat Intensifies
U.S. Envoys Deliver Ultimatum to Ukraine: Sign Peace Deal by Thursday or Risk Losing American Support
Zelenskyy Signals Progress Toward Ending the War: ‘One of the Hardest Moments in History’ (end of his business model?)
U.S. Issues Alert Declaring Venezuelan Airspace a Hazard Due to Escalating Security Conditions
The U.S. State Department Announces That Mass Migration Constitutes an Existential Threat to Western Civilization and Undermines the Stability of Key American Allies
Students Challenge AI-Driven Teaching at University of Staffordshire
Pikeville Medical Center Partners with UK’s Golisano Children’s Network to Expand Pediatric Care
Germany, France and UK Confirm Full Support for Ukraine in US-Backed Security Plan
UK Low-Traffic Neighbourhoods Face Rising Backlash as Pandemic Schemes Unravel
UK Records Coldest Night of Autumn as Sub-Zero Conditions Sweep the Country
UK at Risk of Losing International Doctors as Workforce Exodus Grows, Regulator Warns
ASU Launches ASU London, Extending Its Innovation Brand to the UK Education Market
UK Prime Minister Keir Starmer to Visit China in January as Diplomatic Reset Accelerates
Google Launches Voluntary Buyouts for UK Staff Amid AI-Driven Company Realignment
UK braces for freezing snap as snow and ice warnings escalate
Majority of UK Novelists Fear AI Could Displace Their Work, Cambridge Study Finds
UK's Carrier Strike Group Achieves Full Operational Capability During NATO Drill in Mediterranean
Trump and Mamdani to Meet at the White House: “The Communist Asked”
Nvidia Again Beats Forecasts, Shares Jump in After-Hours Trading
Wintry Conditions Persist Along UK Coasts After Up to Seven Centimetres of Snow
UK Inflation Eases to 3.6 % in October, Opening Door for Rate Cut
UK Accelerates Munitions Factory Build-Out to Reinforce Warfighting Readiness
UK Consumer Optimism Plunges Ahead of November Budget
A Decade of Innovation Stagnation at Apple: The Cook Era Critique
Caribbean Reparations Commission Seeks ‘Mutually Beneficial’ Justice from UK
EU Insists UK Must Contribute Financially for Access to Electricity Market and Broader Ties
UK to Outlaw Live-Event Ticket Resales Above Face Value
President Donald Trump Hosts Saudi Crown Prince Mohammed bin Salman at White House to Seal Major Defence and Investment Deals
German Entertainment Icons Alice and Ellen Kessler Die Together at Age 89
UK Unveils Sweeping Asylum Reforms with 20-Year Settlement Wait and Conditional Status
UK Orders Twitter Hacker to Repay £4.1 Million Following 2020 High-Profile Breach
Popeyes UK Eyes Century Mark as Fried-Chicken Chain Accelerates Roll-out
Two-thirds of UK nurses report working while unwell amid staffing crisis
Britain to Reform Human-Rights Laws in Sweeping Asylum Policy Overhaul
Nearly Half of Job Losses Under Labour Government Affect UK Youth
UK Chancellor Reeves Eyes High-Value Home Levy in Budget to Raise Tens of Billions
UK Urges Poland to Choose Swedish Submarines in Multi-Billion € Defence Bid
US Border Czar Tom Homan Declares UK No Longer a ‘Friend’ Amid Intelligence Rift
UK Announces Reversal of Income Tax Hike Plans Ahead of Budget
Starmer Faces Mounting Turmoil as Leaked Briefings Ignite Leadership Plot Rumours
UK Commentator Sami Hamdi Returns Home After US Visa Revocation and Detention
UK Eyes Denmark-Style Asylum Rules in Major Migration Shift
UK Signals Intelligence Freeze Amid US Maritime Drug-Strike Campaign
TikTok Awards UK & Ireland 2025 Celebrates Top Creators Including Max Klymenko as Creator of the Year
UK Growth Nearly Stalls at 0.1% in Q3 as Cyberattack Halts Car Production
Apple Denied Permission to Appeal UK App Store Ruling, Faces Over £1bn Liability
UK Chooses Wylfa for First Small Modular Reactors, Drawing Sharp U.S. Objection
Starmer Faces Growing Labour Backlash as Briefing Sparks Authority Crisis
×