London Daily

Focus on the big picture.
Tuesday, Sep 01, 2026

Covid: Vaccine complications dwarfed by virus risks

Covid: Vaccine complications dwarfed by virus risks

A major review of vaccines suggests the AstraZeneca jab does raise the risk of blood clots and another serious condition that can cause bleeding.

But the study found the risk of such problems following a coronavirus infection was still much higher.

The University of Oxford-led team also found an increased risk of stroke after the Pfizer jab - but again at a much lower rate than after infection.

The team said it once again showed the "substantial" benefit of vaccination.

It comes after a coroner ruled on Thursday that BBC Radio Newcastle presenter Lisa Shaw died because of complications from the AstraZeneca jab.

The 44-year-old died in May after developing headaches a week after getting her first dose. She suffered blood clots in the brain.

The research team looked at records from more than 29 million people who received a first dose of a Covid vaccine between December and April, who were mostly over 40, as well as nearly 1.8 million who were infected with the virus.

The study, published in the British Medical Journal, looked for complications up to 28 days after being jabbed or infected.

It found that for every 10 million people vaccinated with the AstraZeneca vaccine:

*  an extra 107 would be hospitalised or die from thrombocytopenia, which can cause internal bleeding and haemorrhages, but that was nearly nine times lower than the risk of the same condition following an infection

*  an extra 66 would be hospitalised or die from blood clots in the veins, but that was nearly 200 times lower than the risk following an infection

For every 10 million people vaccinated with the Pfizer vaccine, it found:

*  143 extra strokes would be seen, but that was nearly 12 times lower than the risk following an infection

Lead author Prof Julia Hippisley-Cox said it was important people were aware of the risks, but that they were kept in context given the higher risk from being infected.

Fellow author Prof Aziz Sheikh added the findings "clearly underscore" the importance of getting vaccinated to reduce the risk of these clotting and bleeding outcomes.

Vaccinations, he said, offer a "substantial public health benefit".

None of the university researchers involved in this study were part of the Oxford team that helped develop the AstraZeneca vaccine.


Lead author Prof Julia Hippisley-Cox: "These are really reassuring results"


Newsletter

Related Articles

0:00
0:00
Close
England Faces Renewed Scrutiny Over Sewage Discharges and Water Quality
Victoria Beckham Business Reports First Operating Profit Since Launch
BT Expects £2 Billion From Copper Sales During Full-Fibre Rollout
UK Train Drivers Secure 3.6% Pay Rise and Avert Strike Action
FCA Chief Faces Scrutiny Over Alleged Pressure on Consumer Group in Car Finance Case
Kemi Badenoch Names Andrew Griffith Shadow Chancellor in Conservative Reshuffle
UK House Prices Rise for First Time Since April
UK Shop-Price Inflation Accelerates to 1.5% in August
Met Office Data Point to Hottest UK Summer on Record
UK Announces Emergency Prison Release Measures and £110 Million Capacity Expansion
UK Launches Expanded Free School Meals and 1,400 Breakfast Clubs
Bank of England Governor Warns G20 of AI-Related Economic and Cyber Risks
Prime Minister Andy Burnham Calls for Greater Public Control of Water, Energy and Transport
UK Gains Full Access to £13 Trillion Trans-Pacific Trade Bloc
UK Long-Term Borrowing Costs Hit 28-Year High as Oil Shock Drives Global Bond Selloff
Royal Mail Keeps First-Class Stamps at £1.80 and Second-Class at 91p
Church of England Prepares Formal Apology Over Historical Forced Adoptions
UK Competition Regulator Caps Veterinary Prescription Fees at £21
UK Aviation Authorities Roll Out Airspace Changes to Reduce Flight Delays
England Makes School Allergy Policies Mandatory Under Benedict’s Law
England and Wales Tighten Child Safeguarding Checks by Removing Supervision Exemption
Cornwall Geothermal Plant Begins Commercial Power and Lithium Operations
UK Inflation Holds Near 2.9% as Energy Costs Remain a Risk
UK Productivity Growth Averages 1.1% Over Two Years, Resolution Foundation Says
England Introduces Nationwide School Smartphone Ban and Uniform Limits
UK Gives Border Officers New Powers to Seize Migrants’ Mobile Phones
Green Party Wins First Westminster By-Election in Gorton and Denton
UK and EU Advance Gibraltar Border Deal Allowing Spanish Guards to Conduct Arrival Checks
Robert Jenrick Joins Reform UK After Losing Conservative Whip
Andy Burnham Faces First Prime Minister’s Questions After Labour Cabinet Overhaul
ScottishPower Recycles Nearly All Materials From Historic Hagshaw Hill Wind Farm
Millions Travel Across England, Wales and Northern Ireland for Summer Bank Holiday
Met Office Issues Yellow Thunderstorm Warnings Across Southern England
Four Arrested After Bank Holiday Stabbing Violence in Kettering
Scottish Chamber of Commerce Warns Tax and Business Costs Risk Holding Back Scotland
UK Government Launches Youth Employment Drive With Major Retailers
UK and Ukraine Advance AI and Defence Technology Partnership
Prime Minister Andy Burnham Moves to Exclude Serious Offenders From Early Release
Twelve Arrested After A66 Crash Kills Seven, Including Two Police Officers
Bank of England Governor Warns AI Investment Boom Could Trigger Global Market Correction
London Science Museum Ends Long-Running BP Sponsorship
Scottish Homeowners Prepare Valuation Challenges Over Proposed Mansion Tax
UK Prosecutors Consider Charges Against Undercover Police in Spycops Scandal
James Cleverly Leaves Shadow Cabinet to Run for London Mayor
Avanti West Coast Drivers Agree 3.6% Pay Rise, Averting Strike Action
Allianz Explores £5 Billion Takeover of British Roadside Assistance Group AA
UK Government Retreats From Plan to Unfreeze Personal Income Tax Threshold
Northern Ireland Leaders Press UK Government for Sustainable Funding Settlement
UK Health Agency Warns Nationwide Salmonella Outbreak Could Worsen
NHS Warns Autism and ADHD Assessment Costs Have Become Unsustainable
×