London Daily

Focus on the big picture.
Sunday, Sep 27, 2026

Covid: Vaccine complications dwarfed by virus risks

Covid: Vaccine complications dwarfed by virus risks

A major review of vaccines suggests the AstraZeneca jab does raise the risk of blood clots and another serious condition that can cause bleeding.

But the study found the risk of such problems following a coronavirus infection was still much higher.

The University of Oxford-led team also found an increased risk of stroke after the Pfizer jab - but again at a much lower rate than after infection.

The team said it once again showed the "substantial" benefit of vaccination.

It comes after a coroner ruled on Thursday that BBC Radio Newcastle presenter Lisa Shaw died because of complications from the AstraZeneca jab.

The 44-year-old died in May after developing headaches a week after getting her first dose. She suffered blood clots in the brain.

The research team looked at records from more than 29 million people who received a first dose of a Covid vaccine between December and April, who were mostly over 40, as well as nearly 1.8 million who were infected with the virus.

The study, published in the British Medical Journal, looked for complications up to 28 days after being jabbed or infected.

It found that for every 10 million people vaccinated with the AstraZeneca vaccine:

*  an extra 107 would be hospitalised or die from thrombocytopenia, which can cause internal bleeding and haemorrhages, but that was nearly nine times lower than the risk of the same condition following an infection

*  an extra 66 would be hospitalised or die from blood clots in the veins, but that was nearly 200 times lower than the risk following an infection

For every 10 million people vaccinated with the Pfizer vaccine, it found:

*  143 extra strokes would be seen, but that was nearly 12 times lower than the risk following an infection

Lead author Prof Julia Hippisley-Cox said it was important people were aware of the risks, but that they were kept in context given the higher risk from being infected.

Fellow author Prof Aziz Sheikh added the findings "clearly underscore" the importance of getting vaccinated to reduce the risk of these clotting and bleeding outcomes.

Vaccinations, he said, offer a "substantial public health benefit".

None of the university researchers involved in this study were part of the Oxford team that helped develop the AstraZeneca vaccine.


Lead author Prof Julia Hippisley-Cox: "These are really reassuring results"


Newsletter

Related Articles

0:00
0:00
Close
Analysis of Reform UK conference highlights deep political divisions over welfare and immigration
Bangladesh garment exports to the United Kingdom reach $915 million in early fiscal year
Royal Navy begins sea trials for new HMS Agamemnon hunter-killer submarine
New report suggests UK data centre expansion will create far fewer jobs than predicted
Major weekend closures announced for London Underground Piccadilly and Central lines
NHS leaders call for emergency winter funding to combat staffing shortages and rising illness
Far-right activist Daniel Thomas charged following alleged slashing of migrant dinghy
Home Secretary orders urgent review of border security following rise in small boat crossings
Prime Minister Andy Burnham to address Labour Party conference amid calls for long-term infrastructure plan
UK Treasury and Bank of England warn of rising inflation risks amid Middle East tensions
Royal Navy Diving Squadron Honoured for Global Bomb Disposal Efforts
UK State Pension Set to Approach £13,000 Per Year Under Triple-Lock
Rolls-Royce Wins Multi-Million-Pound Engine Contract with Philippine Airlines
TfL Questions Future of Heathrow Express Amid Proposed £33 Billion Expansion
Ed Miliband Warns Iran Against Hostile Operations on British Soil
S&P Global Manufacturing Index Signals Stabilization Amid Rising Fuel Costs
Prime Minister Andy Burnham Launches National Centre for Information Defence
UK Food and Drink Trade Deficit Surges to £21.1 Billion
OECD Upgrades United Kingdom Economic Growth Forecast to 1.1 Percent
Bank of England Faces Policy Challenges as Energy Prices Push Inflation Projections Higher
IMF Urges UK and Major Economies to Reduce Public Borrowing and Debt
UK Government Concedes Chagos Islands Sovereignty Deal is Dead Following Trump Opposition
Prosecutors Seek More Than 10 Years in Prison for Former DUP Leader Jeffrey Donaldson
UK Provided £66 Million in Emergency Security Funding for Mosques After Southport Disorder
Manston Inquiry Examines Role of Government Decisions in 2022 Overcrowding Crisis
Justice System Capacity Pressures Raise Concerns Over Release of Sex Offenders
UK Food and Drink Trade Deficit Widens to Record £21.1 Billion
UK Releases Climate Security Findings Previously Withheld Under Starmer
TalkTalk Races to Sell Consumer and Broadband Businesses as Administration Threat Looms
NHS Bodies Impose Minimum Two-Year Waits for ADHD and Autism Assessments
Andy Burnham Pledges £210 Million to Revive Boarded-Up High Streets
UK Borrowing Reaches £18.3 Billion in August Ahead of Autumn Budget
Vistry Cuts Profit Outlook as Losses Deepen and Private Home Sales Weaken
Reported Assaults on Great Britain’s Railways Rise Sharply
Far-Right Activist Daniel Thomas Arrested After Channel Dinghy Slashing
Ukrainians in Britain Face Greater Homelessness Risk as Host Payments Are Cut
Scottish Drug Deaths Rise as Synthetic Opioids Spread
UK Diesel Prices Approach Record High as Energy Costs Intensify
UK Food and Drink Trade Deficit Widens to Record £21 Billion
Britain’s Largest Planned AI Supercomputer Delayed by Power Grid Constraints
NHS Boards Impose Minimum Waits of Up to Two Years for ADHD and Autism Assessments
Police Arrest Far-Right Activist After Migrant Dinghy Slashed in English Channel
Synthetic Opioids Drive Renewed Rise in Scotland’s Drug Deaths
Reported Assaults on Britain’s Railways Rise 20% in a Year
Vistry Cuts Profit Forecast as Losses Weigh on UK Housebuilder
TikTok Drops Appeal and Accepts £12.7 Million UK Data Protection Fine
Russell Group Urges UK Government to Drop Proposed International Student Levy
Legal & General Plans to Cut 1,000 Jobs by Mid-2027
UK Health Bill Would Remove Independent Governors From NHS Foundation Trusts
BMA Raises Patient Safety Concerns Over Advanced Practitioners Filling Doctor Rotas
×