London Daily

Focus on the big picture.
Saturday, Dec 20, 2025

Covid: Children 'well protected by Pfizer vaccine'

Covid: Children 'well protected by Pfizer vaccine'

Pfizer says trials of its Covid vaccine in children aged 12 to 15 show 100% efficacy and a strong immune response.

Initial results from trials in 2,260 adolescents in the US also suggest the vaccine is safe with no unusual side-effects.

The drug company says it will submit its data to the US and European authorities for emergency use in 12- to 15-year-olds.

There are currently no plans for children to be vaccinated in the UK.

Children's risk of becoming very ill or even dying with Covid-19 is tiny, and throughout the pandemic they have very rarely needed hospital treatment.

Adults - particularly those over 50 and people with serious underlying health conditions - have a much higher risk, which is why they have been vaccinated as a priority in the UK.

Pfizer is one of a number of drug companies testing their Covid vaccines on children. The aim of vaccinating them - particularly older children - would be to keep schools open, reduce the spread of coronavirus in the community and protect vulnerable children with conditions which put them at increased risk.

AstraZeneca announced trials of its vaccine in UK children aged six to 17 some time ago, and the first of 300 volunteers were due to be jabbed last month. The vaccine is currently only authorised for people aged 18 and over in the UK.

Alongside trials in teenagers, the Pfizer-BioNTech vaccine, which is authorised for use in those aged over 16, is also being tested in children under 12, with the aim of involving babies from just six months old.

The company started dosing the first healthy, young children in this trial last week.

Unknowns


In the Pfizer trial in 12- to 15-year-olds, 18 cases of Covid-19 were seen in the group given a dummy vaccine and none in group given the Covid vaccine which protects against it.

All participants received two doses 21 days apart, and the 18 cases were all children with symptoms. There were no tests for asymptomatic infection - children displaying no symptoms.

The figures are preliminary and full data has not been released, peer-reviewed or published in a journal.

Dr Peter English, former consultant in communicable disease control and past chair of the BMA public health medicine committee, said more detail was needed to properly evaluate the company's claims.

"It would be useful to know how effective the vaccine is at preventing asymptomatic infection. Young people are less likely to have severe disease; and when they are infected, they are more likely to have asymptomatic infection, allowing them to transmit the disease to others," he said.

The company's press release also doesn't mention the impact of variants on the trials, how cases were identified in children and whether a longer gap between doses was tested.


'Next school year'


Albert Bourla, chairman and chief executive officer of Pfizer, said the company was "encouraged" by the clinical trial data.

"We plan to submit these data to FDA [US Federal Drugs Administration] as a proposed amendment to our Emergency Use Authorization in the coming weeks, and to other regulators around the world, with the hope of starting to vaccinate this age group before the start of the next school year."

Ugur Sahin, CEO and co-founder of BioNTech, said the initial results in adolescents suggested children "are particularly well protected by vaccination".

He added: "It is very important to enable them to get back to everyday school life and to meet friends and family while protecting them and their loved ones."

Moderna, the US company behind another Covid vaccine ordered by the UK, has also started testing its jab on children under 11.

Newsletter

Related Articles

0:00
0:00
Close
Women in Partial Nudity — and Bill Clinton in a Dress and Heels: The Images Revealed in the “Epstein Files”
US Envoy Witkoff to Convene Security Advisers from Ukraine, UK, France and Germany in Miami as Peace Efforts Intensify
UK Retailers Report Sharp Pre-Christmas Sales Decline and Weak Outlook, CBI Survey Shows
UK Government Rejects Use of Frozen Russian Assets to Fund Aid for Ukraine
UK Financial Conduct Authority Opens Formal Investigation into WH Smith After Accounting Errors
UK Issues Final Ultimatum to Roman Abramovich Over £2.5bn Chelsea Sale Funds for Ukraine
Rare Pink Fog Sweeps Across Parts of the UK as Met Office Warns of Poor Visibility
UK Police Pledge ‘More Assertive’ Enforcement to Tackle Antisemitism at Protests
UK Police Warn They Will Arrest Protesters Chanting ‘Globalise the Intifada’
Trump Files $10 Billion Defamation Lawsuit Against BBC as Broadcaster Pledges Legal Defence
UK Says U.S. Tech Deal Talks Still Active Despite Washington’s Suspension of Prosperity Pact
UK Mortgage Rules to Give Greater Flexibility to Borrowers With Irregular Incomes
UK Treasury Moves to Position Britain as Leading Global Hub for Crypto Firms
U.S. Freezes £31 Billion Tech Prosperity Deal With Britain Amid Trade Dispute
Prince Harry and Meghan’s Potential UK Return Gains New Momentum Amid Security Review and Royal Dialogue
Zelensky Opens High-Stakes Peace Talks in Berlin with Trump Envoy and European Leaders
Historical Reflections on Press Freedom Emerge Amid Debate Over Trump’s Media Policies
UK Boosts Protection for Jewish Communities After Sydney Hanukkah Attack
UK Government Declines to Comment After ICC Prosecutor Alleges Britain Threatened to Defund Court Over Israel Arrest Warrant
Apple Shutters All Retail Stores in the United Kingdom Under New National COVID-19 Lockdown
US–UK Technology Partnership Strains as Key Trade Disagreements Emerge
UK Police Confirm No Further Action Over Allegation That Andrew Asked Bodyguard to Investigate Virginia Giuffre
Giuffre Family Expresses Deep Disappointment as UK Police Decline New Inquiry Into Andrew Mountbatten-Windsor Claims
Transatlantic Trade Ambitions Hit a Snag as UK–US Deal Faces Emerging Challenges
Ex-ICC Prosecutor Alleges UK Threatened to Withdraw Funding Over Netanyahu Arrest Warrant Bid
UK Disciplinary Tribunal Clears Carter-Ruck Lawyer of Misconduct in OneCoin Case
‘Pink Ladies’ Emerge as Prominent Face of UK Anti-Immigration Protests
Nigel Farage Says Reform UK Has Become Britain’s Largest Party as Labour Membership Falls Sharply
Google DeepMind and UK Government Launch First Automated AI Lab to Accelerate Scientific Discovery
UK Economy Falters Ahead of Budget as Growth Contracts and Confidence Wanes
Australia Approves Increased Foreign Stake in Strategic Defence Shipbuilder
Former UK Prime Minister Boris Johnson proclaims, “For Ukraine, surrendering their land would be a nightmare.”
Microsoft Challenges £2.1 Billion UK Cloud Licensing Lawsuit at Competition Tribunal
Fake Doctor in Uttar Pradesh Accused of Killing Woman After Performing YouTube-Based Surgery
Hackers Are Hiding Malware in Open-Source Tools and IDE Extensions
Traveling to USA? Homeland Security moving toward requiring foreign travelers to share social media history
UK Officials Push Back at Trump Saying European Leaders ‘Talk Too Much’ About Ukraine
UK Warns of Escalating Cyber Assault Linked to Putin’s State-Backed Operations
UK Consumer Spending Falters in November as Households Hold Back Ahead of Budget
UK Orders Fresh Review of Prince Harry’s Security Status After Formal Request
U.S. Authorises Nvidia to Sell H200 AI Chips to China Under Security Controls
Trump in Direct Assault: European Leaders Are Weak, Immigration a Disaster. Russia Is Strong and Big — and Will Win
"App recommendation" or disguised advertisement? ChatGPT Premium users are furious
"The Great Filtering": Australia Blocks Hundreds of Thousands of Minors From Social Networks
Mark Zuckerberg Pulls Back From Metaverse After $70 Billion Loss as Meta Shifts Priorities to AI
Nvidia CEO Says U.S. Data-Center Builds Take Years while China ‘Builds a Hospital in a Weekend’
Indian Airports in Turmoil as IndiGo Cancels Over a Thousand Flights, Stranding Thousands
Hollywood Industry on Edge as Netflix Secures Near-$60 Bln Loan for Warner Bros Takeover
Drugs and Assassinations: The Connection Between the Italian Mafia and Football Ultras
Hollywood megadeal: Netflix acquires Warner Bros. Discovery for 83 billion dollars
×