London Daily

Focus on the big picture.
Monday, Aug 24, 2026

Britain to Deliberately Infect Volunteers With Coronavirus

Britain to Deliberately Infect Volunteers With Coronavirus

Healthy volunteers will be deliberately infected with the coronavirus to try to speed up the development of a vaccine, under plans announced by the British government this week.

The trial will involve healthy volunteers ages 18 to 30.

Most coronavirus vaccine trials involve giving volunteers the potential vaccine or a placebo and then waiting until enough of them have been exposed to the virus through their everyday lives. That can take months or years.

Britain announced this week it plans to begin the so-called "human challenge" trials in May 2021 to speed up the development of vaccines.

Several young people have already volunteered, among them Danica Marcos, 22, a recent university graduate from London.

"So many people [are] struggling right now. I want this pandemic to be over," Marcos told The Associated Press. "Every day that goes on, more cases are going on, more people are dying. And if this vaccine trial could mean that this period of trauma for the whole world will be over sooner, I want to help. I want to be a part of that."


People walk past a display featuring health advice in the shopping district in central Sheffield, south Yorkshire, Oct. 21, 2020.


Alastair Fraser-Urqhart, 18, from Stoke-on-Trent said he wanted to contribute to a vaccine.

"Personally, I can't let this opportunity to do something, to really do something, pass me by when I'm at such low risk than other people," he said.

The British government plans to invest over $43.4 million in the challenge trial. The World Health Organization said it could be significant.

"There is a very long history of this for development of a number of vaccines that has been part of what has gone on with, say, the development of the cholera vaccines and the typhoid vaccines," said Margaret Harris, a spokeswoman for WHO.

Harris also expressed some concerns.

"What is critical is that if people are considering this, it must be overseen by an ethics committee, and the volunteers must have full consent, and they must select the volunteers in order to minimize their risk. Because you will be challenging people with a virus that we do not have a treatment for," Harris said.

"So, you must ensure that everybody involved understands exactly what is at stake, must be selected to minimize the risk. The volunteer and you must ensure that informed consent is rigorous, that they really do understand all the risks."


A passenger in a car receives a novel coronavirus test at a drive-in COVID-19 testing facility set up at the Chessington World of Adventures Resort, in Chessington, southwest of London, Oct. 20, 2020.


Infections, hospitalizations and deaths from the new coronavirus are rising sharply in many countries around the world. A vaccine remains the best hope of any return to some kind of normality, said Dr. Sterghios Moschos, a microbiologist at the University of Northumbria, who spoke to VOA in a recent interview.

"At this point in time, we don't have a way of stopping transmission," Moschos said. "And we don't even have the financial capacity to give multiple antibody treatments, steroids, et cetera, like Donald Trump received, to everybody in the population that needs treatment. The cost is quite large for these kinds of treatments. We don't have a vaccine. And therefore, as a result, we need to contain the spread of this virus. Not just manage it, contain it."

The initial aim of the British research team will be to discover the smallest amount of virus it takes to cause a COVID-19 infection, using controlled doses of the virus. If approved by regulators and an ethics committee, it is hoped the full challenge trial could begin in May 2021.

Newsletter

Related Articles

0:00
0:00
Close
Prime Minister Andy Burnham to Give Ukraine Classified Storm Shadow Blueprints for Domestic Missile Production
UK Graduate Job Vacancies Plunge 45% to Lowest Levels on Record
Government Audit Reveals Pressure on UK Hospitality From Business Rates and Rising Costs
Kindertransport Survivor Prepares to Revisit European Sites Linked to Her Family’s Wartime Separation
Northern England Transport Operators Strengthen Contingency Plans as Travel Demand Rises
New Implant Trials Offer Treatment Prospects for Patients With Refractory Angina
South Wales Reviews Wildfire Response After Exceptionally Dry Summer
UK Treasury Prepares Autumn Fiscal Statement Amid Spending and Defense Pressures
Norfolk Records First Wild Beaver Births in More Than Five Hundred Years
Historic Portrait of Benjamin Disraeli Reported Missing From Parliament’s Art Collection
Five People, Including Police Officers, Killed in A66 Crash as Families Pay Tribute
Most English Secondary Schools Found to Fall Short of National Healthy Food Standards
UK Think Tank Says Productivity Growth May Be Stronger Than Official Data Shows
Reform Party Proposes Lower Social Housing Priority for Foreign-Born UK Citizens
UK Government Plans Business Rate Overhaul to Ease Pressure on Pubs and Hotels
New Daily Diabetes and Weight-Loss Pill Launches Across NHS Pharmacies in England
UK Graduate Job Vacancies Fall to Lowest Level in a Decade
UK Prime Minister Andy Burnham Visits Kyiv to Reaffirm Long-Term Military Support for Ukraine
Iranian Hackers Shut Down British Power Plant for Four Days in Landmark Cyber Attack
Novak Djokovic Reveals Relentless Self-Doubt and Rejects Retirement in New Documentary
Trump Imposes 50% Tariffs on Canadian Goods After Bilateral Trade Talks Collapse
First Bus Bars Unaccompanied Under-Sixteens From Evening Services in Stoke-on-Trent
Lithium-Ion Battery Fires Cost UK Waste Sector About One Billion Pounds a Year
Reform UK Proposes Lower Social Housing Priority for Foreign-Born Naturalised Citizens
UK Government Deploys AI Drones in Crackdown on Illegal Waste Dumping
EU Biometric Border Checks Cause Disruption for British Travellers and Freight Operators
UK Expands Voluntary Drug Treatment Programme for Sex Offenders to Twenty Prisons
CrossCountry Cancels Most Services After Major Power Failure at Control Centre
Met Office Warns El Niño Could Bring Severe Autumn Storms and Higher Food Prices
Resolution Foundation Says UK Productivity Growth May Be Stronger Than Official Data Suggest
Andy Burnham Proposes Giving Regional Mayors Greater Planning Powers
UK Government Overhauls Planning Rules to Accelerate Housing Near Transport Links
Russia Withdraws Ambassador to Britain and Warns of Retaliation Over UK Drone Supplies to Ukraine
Iran-Linked Hackers Blamed for Cyberattack That Shut Down UK Power Plant
Andy Burnham Pledges UK Support for Long-Range Missile Production in Ukraine
Australia Combines Indigenous Fire Knowledge With Satellite Tech to Combat Catastrophic Wildfires
Father and Son Jailed in Scotland Over £900,000 Airport Cannabis Smuggling Operation
UK Fraud Reports Surge Sevenfold as Criminals Exploit QR Codes in Parking Meters and Phishing Emails
Brighton Thrash Aston Villa in Four-Goal Opening Half as Manchester City Trail Bournemouth
Erin Patterson Appeals Triple Murder Convictions After Hotel Mixed Sequestered Jury With Prosecution
Bank of England Maintains Close Watch on Banks Amid Global Economic Uncertainty
Warm Weather and Tourism Support UK High Street Spending During Summer
Westminster Faces Continuing Political and Administrative Fallout From Epstein Files Release
UK Invests in Domestic Defence Drone Manufacturing to Strengthen Military Supply Chains
Around Five Million UK Households Face Higher Mortgage Payments by 2028
Bluetongue Virus Cases Rise Across England, Wales and Scotland
UK Government Holds First National Day for Victims and Survivors of Terrorism
Historic Summer Droughts Threaten UK Harvests and Put Further Pressure on Food Prices
UK Economy Holds Up in Second Quarter Despite Global Energy and Geopolitical Pressures
UK Opens National Artificial Intelligence Safety Testing Facility
×