London Daily

Focus on the big picture.
Monday, Nov 10, 2025

What it does to the body

The coronavirus emerged in only December last year, but already the world is dealing with a pandemic of the virus and the disease it causes - Covid-19.

For most, the disease is mild, but some people die.

So how is the virus attacking the body, why are some people being killed and how is it treated?


Incubation period

This is when the virus is establishing itself.

Viruses work by getting inside the cells your body is made of and then hijacking them.

The coronavirus, officially called Sars-CoV-2, can invade your body when you breathe it in (after someone coughs nearby) or you touch a contaminated surface and then your face.

It first infects the cells lining your throat, airways and lungs and turns them into "coronavirus factories" that spew out huge numbers of new viruses that go on to infect yet more cells.

At this early stage, you will not be sick and some people may never develop symptoms.

The incubation period, the time between infection and first symptoms appearing, varies widely, but is five days on average.


Mild disease

This is all most people will experience.

Covid-19 is a mild infection for eight out of 10 people who get it and the core symptoms are a fever and a cough.

Body aches, sore throat and a headache are all possible, but not guaranteed.

The fever, and generally feeling grotty, is a result of your immune system responding to the infection. It has recognised the virus as a hostile invader and signals to the rest of the body something is wrong by releasing chemicals called cytokines.

These rally the immune system, but also cause the body aches, pain and fever.

The coronavirus cough is initially a dry one (you're not bringing stuff up) and this is probably down to irritation of cells as they become infected by the virus.

Some people will eventually start coughing up sputum - a thick mucus containing dead lung cells killed by the virus.

These symptoms are treated with bed rest, plenty of fluids and paracetamol. You won't need specialist hospital care.

This stage lasts about a week - at which point most recover because their immune system has fought off the virus.

However, some will develop a more serious form of Covid-19.

This is the best we understand at the moment about this stage, however, there are studies emerging that suggest the disease can cause more cold-like symptoms such as a runny nose too.


Severe disease

If the disease progresses it will be due to the immune system overreacting to the virus.

Those chemical signals to the rest of the body cause inflammation, but this needs to be delicately balanced. Too much inflammation can cause collateral damage throughout the body.

"The virus is triggering an imbalance in the immune response, there's too much inflammation, how it is doing this we don't know," said Dr Nathalie MacDermott, from King's College London.

Inflammation of the lungs is called pneumonia.

If it was possible to travel through your mouth down the windpipe and through the tiny tubes in your lungs, you'd eventually end up in tiny little air sacs.

This is where oxygen moves into the blood and carbon dioxide moves out, but in pneumonia the tiny sacs start to fill with water and can eventually cause shortness of breath and difficulty breathing.

Some people will need a ventilator to help them breathe.

This stage is thought to affect around 14% of people, based on data from China.


Critical disease

It is estimated around 6% of cases become critically ill.

By this point the body is starting to fail and there is a real chance of death.

The problem is the immune system is now spiralling out of control and causing damage throughout the body.

It can lead to septic shock when the blood pressure drops to dangerously low levels and organs stop working properly or fail completely.

Acute respiratory distress syndrome caused by widespread inflammation in the lungs stops the body getting enough oxygen it needs to survive. It can stop the kidneys from cleaning the blood and damage the lining of your intestines.

"The virus sets up such a huge degree of inflammation that you succumb... it becomes multi-organ failure," Dr Bharat Pankhania said.

And if the immune system cannot get on top of the virus, then it will eventually spread to every corner of the body where it can cause even more damage.

Treatment by this stage will be highly invasive and can include ECMO or extra-corporeal membrane oxygenation.

This is essentially an artificial lung that takes blood out of the body through thick tubes, oxygenates it and pumps it back in.

But eventually the damage can reach fatal levels at which organs can no longer keep the body alive.


The first deaths

Doctors have described how some patients died despite their best efforts.

The first two patients to die at Jinyintan Hospital in Wuhan, China, detailed in the Lancet Medical journal, were seemingly healthy, although they were long-term smokers and that would have weakened their lungs.

The first, a 61-year-old man, had severe pneumonia by the time he arrived at hospital.

He was in acute respiratory distress, and despite being put on a ventilator, his lungs failed and his heart stopped beating.

He died 11 days after he was admitted.

The second patient, a 69-year-old man, also had acute respiratory distress syndrome.

He was attached to an ECMO machine but this wasn't enough. He died of severe pneumonia and septic shock when his blood pressure collapsed.

Newsletter

Related Articles

0:00
0:00
Close
Tom Cruise Arrives by Helicopter at UK Scientology Fundraiser Amid Local Protests
Prince Andrew and Sarah Ferguson Face Fresh UK Probes Amid Royal Fallout
Mothers Link Teen Suicides to AI Chatbots in Growing Legal Battle
UK Government to Mirror Denmark’s Tough Immigration Framework in Major Policy Shift
UK Government Turns to Denmark-Style Immigration Reforms to Overhaul Border Rules
UK Chancellor Warned Against Cutting Insulation Funding as Budget Looms
UK Tenant Complaints Hit Record Levels as Rental Sector Faces Mounting Pressure
Apple to Pay Google About One Billion Dollars Annually for Gemini AI to Power Next-Generation Siri
UK Signals Major Shift as Nuclear Arms Race Looms
BBC’s « Celebrity Traitors UK » Finale Breaks Records with 11.1 Million Viewers
UK Spy Case Collapse Highlights Implications for UK-Taiwan Strategic Alignment
On the Road to the Oscars? Meghan Markle to Star in a New Film
A Vote Worth a Trillion Dollars: Elon Musk’s Defining Day
AI Researchers Claim Human-Level General Intelligence Is Already Here
President Donald Trump Challenges Nigeria with Military Options Over Alleged Christian Killings
Nancy Pelosi Finally Announces She Will Not Seek Re-Election, Signalling End of Long Congressional Career
UK Pre-Budget Blues and Rate-Cut Concerns Pile Pressure on Pound
ITV Warns of Nine-Per-Cent Drop in Q4 Advertising Revenue Amid Budget Uncertainty
National Grid Posts Slightly Stronger-Than-Expected Half-Year Profit as Regulatory Investments Drive Growth
UK Business Lobby Urges Reeves to Break Tax Pledges and Build Fiscal Headroom
UK to Launch Consultation on Stablecoin Regulation on November 10
UK Savers Rush to Withdraw Pension Cash Ahead of Budget Amid Tax-Change Fears
Massive Spoilers Emerge from MAFS UK 2025: Couple Swaps, Dating App Leaks and Reunion Bombshells
Kurdish-led Crime Network Operates UK Mini-Marts to Exploit Migrants and Sell Illicit Goods
UK Income Tax Hike Could Trigger £1 Billion Cut to Scotland’s Budget, Warns Finance Secretary
Tommy Robinson Acquitted of Terror-related Charge After Phone PIN Dispute
Boris Johnson Condemns Western Support for Hamas at Jewish Community Conference
HII Welcomes UK’s Westley Group to Strengthen AUKUS Submarine Supply Chain
Tragedy in Serbia: Coach Mladen Žižović Collapses During Match and Dies at 44
Diplo Says He Dated Katy Perry — and Justin Trudeau
Dick Cheney, Former U.S. Vice President, Dies at 84
Trump Calls Title Removal of Andrew ‘Tragic Situation’ Amid Royal Fallout
UK Bonds Rally as Chancellor Reeves Briefs Markets Ahead of November Budget
UK Report Backs Generational Smoking Ban Ahead of Tobacco & Vapes Bill Review
UK’s Domino’s Pizza Group Reports Modest Like-for-Like Sales Growth in Q3
UK Supplies Additional Storm Shadow Missiles to Ukraine as Trump Alleges Russian Underground Nuclear Tests
High-Profile Broodmare Puca Sells for Five Million Dollars at Fasig-Tipton ‘Night of the Stars’
Wilt Chamberlain’s One-of-a-Kind ‘Searcher 1’ Supercar Heads to Auction
Erling Haaland’s Remarkable Run: 13 Premier League Goals in 10 Matches and Eyes on History
UK Labour Peer Warns of Emerging ‘Constituency for Hating Jews’ in Britain
UK Home Secretary Admits Loss of Border Control, Warns Public Trust at Risk
President Trump Expresses Sympathy for UK Royal Family After Title Stripping of Prince Andrew
Former Prince Andrew to Lose His Last Military Title as King Charles Moves to End His Public Role
King Charles Relocates Andrew to Sandringham Estate and Strips Titles Amid Epstein Fallout
Two Arrested After Mass Stabbing on UK Train Leaves Ten Hospitalised
Glamour UK Says ‘Stay Mad Jo x’ After Really Big Rowling Backlash
Former Prince Prince Andrew Faces Possible U.S. Congressional Appearance Over Jeffrey Epstein Inquiry
UK Faces £20 Billion Productivity Shortfall as Brexit’s Impact Deepens
UK Chancellor Rachel Reeves Eyes New Council-Tax Bands for High-Value Homes
UK Braces for Major Storm with Snow, Heavy Rain and Winds as High as 769 Miles Wide
×