London Daily

Focus on the big picture.
Saturday, Jan 31, 2026

The Bill & Melinda Gates Foundation partly funded an Omicron variant study with a surprising conclusion about boosters

The Bill & Melinda Gates Foundation partly funded an Omicron variant study with a surprising conclusion about boosters

The latest Omicron subvariant may be a master at evading the immune response our bodies produce from the vaccine or previous COVID-19 infection, but a new study suggests existing booster shots will still help.
Getting a booster can generate enough of an antibody response and protection from severe disease outcomes to hold up against any of the new Omicron subvariants, according to an early release paper published this week in Science. That extends to BA.5, now the most prevalent COVID strain in the U.S. and a driver of COVID-19 reinfections across the country.

The finding comes as the Biden administration considers whether to expand access to a second booster shot to all adults because of concerns that subvariants BA.4 and BA.5 will further push up cases and hospitalizations. Since March, anyone 50 and older or immunocompromised and at least 12 years old has been eligible for a second booster, per CDC recommendations.

Led by the University of Washington School of Medicine’s Veesler Lab, the research team started a few months ago by just looking at the previously dominant BA.1, BA.2, and BA.2.12.1 subvariants, then later adding in BA.4 and BA.5. It assessed the properties of these subvariants and evaluated how a panel of seven vaccines already available in the U.S. and around the globe would protect against them.

BA.5 is a relatively new Omicron subvariant but “probably the most important one now in the study as it’s about to become globally dominant,” according to John Bowen, one of the paper’s lead authors and a biochemist at the Veesler Lab.

The BA.5 strain has been touted as the most contagious one yet, so much so that vaccinated people have reported catching it even after a recent bout of COVID-19. The first part of the study sheds light on why that is; BA.5 can outcompete other subvariants because its spike protein binds to the host receptor more than six times better than the original strain that first circulated in 2019.

The researchers ultimately determined that BA.5 will be the most immune-evasive COVID-19 variant to date, but that doesn’t mean our previous boosters can no longer restore protection.

“We were able to look at essentially every single prominent vaccine platform in the world side by side and see that despite the scariness of this variant, all of these vaccine platforms are going to elicit solid immune responses,” Bowen told Fortune.

Because of BA.5’s reputation, the findings initially caught the researcher by surprise.

“When I was seeing the data after the third shot, I had to repeat it over and over again because I was just like, ‘Why am I not seeing that this is as immune evasive as other people have said?’” Bowen recounted. “We were very excited to see that even though it’s more immune evasive than the other ones we tested, previous methods are still going to protect against it.”

The research effort was an international collaboration between infectious disease research physicians and scientists from UW Medicine, the Fred Hutchinson Cancer Center in Seattle, and institutes in California, Argentina, Italy, Pakistan, and Switzerland. It received funding from a plethora of sources, including the Bill & Melinda Gates Foundation and the National Institute of Allergy and Infectious Diseases.

The Food and Drug Administration has advised vaccine makers to update their booster shots to target the BA.4 and BA.5 Omicron subvariants. While people wait for those, though, Bowen said the research indicates that vaccines designed for a strain from a few years ago still work.

“We totally agree it’s very important to continue trying to find better ways to make protective vaccines,” he said. “It’s going to take some time to get those. If people need vaccines, we know that current boosting methods are going to be protective.”
Comments

Oh ya 4 year ago
And the stupid people will line up for this like sheep to the slaughter. Use you brains folks if the first 3 clot shots did not protect you and they have not changed the so called vaccine do you really thing shot 4 will be the magic bullet. If you think it will protect you then please go take it as we know the shots are removing stupid people from the gene pool at a huge rate. You just can not fix stupid.

Newsletter

Related Articles

0:00
0:00
Close
France Begins Phasing Out Zoom and Microsoft Teams to Advance Digital Sovereignty
China Lifts Sanctions on British MPs and Peers After Starmer Xi Talks in Beijing
Trump Nominates Kevin Warsh as Fed Chair to Reorient U.S. Monetary Policy Toward Pro-Growth Interest Rates
AstraZeneca Announces £11bn China Investment After Scaling Back UK Expansion Plans
Starmer and Xi Forge Warming UK-China Ties in Beijing Amid Strategic Reset
Tech Market Shifts and AI Investment Surge Drive Global Innovation and Layoffs
Markets Jolt as AI Spending, US Policy Shifts, and Global Security Moves Drive New Volatility
U.S. Signals Potential Decertification of Canadian Aircraft as Bilateral Tensions Escalate
Former South Korean First Lady Kim Keon Hee Sentenced to 20 Months for Bribery
Tesla Ends Model S and X Production and Sends $2 Billion to xAI as 2025 Revenue Declines
China Executes 11 Members of the Ming Clan in Cross-Border Scam Case Linked to Myanmar’s Lawkai
Trump Administration Officials Held Talks With Group Advocating Alberta’s Independence
Starmer Signals UK Push for a More ‘Sophisticated’ Relationship With China in Talks With Xi
Shopping Chatbots Move From Advice to Checkout as Walmart Pushes Faster Than Amazon
Starmer Seeks Economic Gains From China Visit While Navigating US Diplomatic Sensitivities
Starmer Says China Visit Will Deliver Economic Benefits as He Prepares to Meet Xi Jinping
UK Prime Minister Starmer Arrives in China to Bolster Trade and Warn Firms of Strategic Opportunities
The AI Hiring Doom Loop — Algorithmic Recruiting Filters Out Top Talent and Rewards Average or Fake Candidates
Amazon to Cut 16,000 Corporate Jobs After Earlier 14,000 Reduction, Citing Streamlining and AI Investment
Federal Reserve Holds Interest Rate at 3.75% as Powell Faces DOJ Criminal Investigation During 2026 Decision
Putin’s Four-Year Ukraine Invasion Cost: Russia’s Mass Casualty Attrition and the Donbas Security-Guarantee Tradeoff
Wall Street Bets on Strong US Growth and Currency Moves as Dollar Slips After Trump Comments
UK Prime Minister Traveled to China Using Temporary Phones and Laptops to Limit Espionage Risks
Google’s $68 Million Voice Assistant Settlement Exposes Incentives That Reward Over-Collection
Kim Kardashian Admits Faking Paparazzi Visit to Britney Spears for Fame in Early 2000s
UPS to Cut 30,000 More Jobs by 2026 Amid Shift to High-Margin Deliveries
France Plans to Replace Teams and Zoom Across Government With Homegrown Visio by 2027
Trump Removes Minneapolis Deportation Operation Commander After Fatal Shooting of Protester
Iran’s Elite Wealth Abroad and Sanctions Leakage: How Offshore Luxury Sustains Regime Resilience
U.S. Central Command Announces Regional Air Exercise as Iran Unveils Drone Carrier Footage
Four Arrested in Andhra Pradesh Over Alleged HIV-Contaminated Injection Attack on Doctor
Hot Drinks, Hidden Particles: How Disposable Cups Quietly Increase Microplastic Exposure
UK Banks Pledge £11 Billion Lending Package to Help Firms Expand Overseas
Suella Braverman Defects to Reform UK, Accusing Conservatives of Betrayal on Core Policies
Melania Trump Documentary Sees Limited Box Office Traction in UK Cinemas
Meta and EssilorLuxottica Ray-Ban Smart Glasses and the Non-Consensual Public Recording Economy
WhatsApp Develops New Meta AI Features to Enhance User Control
Germany Considers Gold Reserves Amidst Rising Tensions with the U.S.
Michael Schumacher Shows Significant Improvement in Health Status
Greenland’s NATO Stress Test: Coercion, Credibility, and the New Arctic Bargaining Game
Diego Garcia and the Chagos Dispute: When Decolonization Collides With Alliance Power
Trump Claims “Total” U.S. Access to Greenland as NATO Weighs Arctic Basing Rights and Deterrence
Air France and KLM Suspend Multiple Middle East Routes as Regional Tensions Disrupt Aviation
U.S. winter storm triggers 13,000-plus flight cancellations and 160,000 power outages
Poland delays euro adoption as Domański cites $1tn economy and zloty advantage
White House: Trump warns Canada of 100% tariff if Carney finalizes China trade deal
PLA opens CMC probe of Zhang Youxia, Liu Zhenli over Xi authority and discipline violations
ICE and DHS immigration raids in Minneapolis: the use-of-force accountability crisis in mass deportation enforcement
UK’s Starmer and Trump Agree on Urgent Need to Bolster Arctic Security
Starmer Breaks Diplomatic Restraint With Firm Rebuke of Trump, Seizing Chance to Advocate for Europe
×