London Daily

Focus on the big picture.
Monday, May 18, 2026

Scientists develop new test that reliably predicts return or spread of deadliest skin cancer

Scientists develop new test that reliably predicts return or spread of deadliest skin cancer

The test, known as AMBLor, is applied to a standard biopsy of the primary melanoma when it is removed and will identify patients who are at low risk of cancer reoccurring or spreading.

Scientists have developed a new test that reliably predicts the spread, or return, of the deadliest form of skin cancer.

The technological advance followed a breakthrough in understanding the mechanisms of skin cancer growth.

More than 16,000 people in the UK and 96,000 people in the US are diagnosed with melanoma every year.

Professor Penny Lovat, who led the work on the test, said it will reassure patients who are less at risk of the disease spreading.

The test, known as AMBLor, is applied to a standard biopsy of the primary melanoma when it is removed and will identify patients who are at low risk of cancer reoccurring or spreading.

It provides anyone diagnosed with a non-ulcerated early-stage melanoma - accounting for around 75% of all new diagnoses - with more accurate information.

"Our test offers a personalised prognosis as it more accurately predicts if your skin cancer is unlikely to spread," said Professor Lovat, of Newcastle University.

"This test will aid clinicians to identify genuinely low-risk patients diagnosed with an early-stage melanoma and to reduce the number of follow-up appointments for those identified as low risk, saving the NHS time and money."

The British Skin Foundation supported the research, done in association with the university spin-out firm Amlo Biosciences.

The foundation's chief operating officer, Phil Brady, said: "The development of the AMBLor test can alleviate stress and anxiety for patients caused by this potentially deadly skin cancer, whilst increasing efficiency and reducing costs to the NHS."

The team has applied to make the test available on the NHS.

Cory Inglis, 49, had a biopsy for a melanoma which will be sent for analysis in the new AMBLor test.

He said the test "helps significantly with the anxiety of an already very stressful situation".

Currently, primary tumours are removed by surgery and pathologists study the biopsy under the microscope to determine the stage the skin cancer is at and the risk of it spreading.

Even if defined as low risk, the patient is followed up in a clinic for as long as five years - and it is these patients that the test is able to identify.

Newsletter

Related Articles

0:00
0:00
Close
'They're people from all walks of life across the UK'
EU Digital ID Claims Misstate What Brussels Can Legally Force on Member States
The Great Western Exit: Why Best Citizens Are Fleeing the Rich World [PODCAST]
The New Robber Barons of Intelligence: Are AI Bosses More Powerful Than Rockefeller?
The End of the Old Order [Podcast]
Britain’s Democracy Is Now a Costume
The AI Gold Rush Is Coming for America’s Last Open Spaces [Podcast]
The Pentagon’s AI Squeeze: Eight Tech Giants Get In, Anthropic Gets Shut Out [Podcast]
The War Map: Professor Jiang’s Dark Theory of Iran, Trump, China, Russia, Israel, and the Coming Global Shock [Podcast]
Labour Is No Longer a National Party [Podcast]
AI Isn’t Stealing Your Job. It’s Dismantling It Piece by Piece.
Lawyers vs Engineers: Why China Builds While America Litigates [Podcast]
Churchill’s Glass: The Drunk, the Doctor, and the Myth Britain Refuses to Sober Up From
Apple issues an unusual warning: this is how your iPhone can be hacked without you doing anything
Kennedy’s Quiet War on Antidepressants Sparks Alarm Across America’s Medical Establishment
The Met Gala Meets the Age of Billionaire Backlash
Russian Oligarch’s Superyacht Crosses Hormuz via Iran-Controlled Route
Gunfire Disrupts White House Correspondents’ Dinner as Trump Is Evacuated
A Leak, a King, and a Fracturing Alliance
Inside the Gates Foundation Turmoil: Layoffs, Scrutiny, and the Cost of Reputational Risk
UK Biobank Breach Exposes Health Data of 500,000, Listed for Sale on Chinese Platform
KPMG Cuts Around 10% of US Audit Partners After Failed Exit Push
French Police Probe Suspected Weather-Data Tampering After Unusual Polymarket Bets on Paris Temperatures
CATL Unveils Revolutionary EV Battery Tech: 1000 km Range and 7-Minute Charging Ahead of Beijing Auto Show
Crypto Scammers Capitalize on Maritime Chaos Near the Strait of Hormuz: A Rising Threat to Shipping Companies
Changi Airport: How Singapore Engineered the World’s Most Efficient Travel Experience
Power Dynamics: Apple’s Leadership Shakeup, Geopolitical Risks in the Strait of Hormuz, and Europe's Energy Strategy Amidst Global Challenges
Apple's Leadership Transition: Can New CEO John Ternus Navigate AI Challenges and Geopolitical Pressures?
Italy’s €100K Tax Gambit: Europe’s Soft Power Tax Haven
News Roundup
Microsoft lost 2.5 millions users (French government) to Linux
Privacy Problems in Microsoft Windows OS
News roundup
Péter András Magyar and the Strategic Reset of Hungary
Hungary After the Landslide — A Strategic Reset in Europe
Meghan Markle Plans Exclusive Women-Focused Retreat During Australia Visit
Starmer and Trump Hold Strategic Talks on Securing Strait of Hormuz Amid Rising Tensions
Unofficial Australia Visit by Prince Harry and Meghan Expected to Stir Tensions with Royal Circles
Pipeline Attack Cuts Significant Share of Saudi Arabia’s Oil Export Capacity
UK Stocks Rise on Ceasefire Momentum and Renewed Focus on Diplomacy
UK to Hold Further Strategic Talks on Strait of Hormuz Security
Starmer Voices Frustration as Global Tensions Drive Up UK Energy Costs
UK Students Voice Concern Over Proposal for Automatic Military Draft Registration
Rising Volatility Drives Uncertainty in UK Fuel and Petrol Prices
UK Moves to Deploy ‘Skyhammer’ Anti-Drone System to Strengthen Airspace Defense
New Analysis Explores UK Budget Mechanics in ‘Behind the Blue’ Feature
Man Arrested After Four Die in Channel Crossing Tragedy
UK Tightens Immigration Framework with New Sponsor Rules and Fee Increases
UK Foreign Secretary Highlights Impact of Intensified Strikes in Lebanon
UK Urges Inclusion of Lebanon in US-Iran Ceasefire Framework
×