London Daily

Focus on the big picture.
Thursday, Dec 04, 2025

Israel’s grand booster vaccine experiment as the world watches on

Israel’s grand booster vaccine experiment as the world watches on

As Covid cases spike, Israel is embarking upon the world’s first vaccine booster programme. Will it work - and what happens if it doesn’t? By Anshel Pfeffer

The only person who kept calm in the packed health clinic in northern Jerusalem on Monday morning was a 19-year-old military medic. As dozens jostled in the narrow corridor leading to the vaccination booths, arguing over whose turn it was next, he surveyed the scene wryly before sitting back in his booth and preparing a syringe with 0.3 millilitres of the Pfizer-BioNTech vaccine which he then plunged into my shoulder.

“This is actually a lull,” he said. “You should have been here an hour ago when the real chaos began.” Perhaps for the soldier — seconded the previous week from his combat engineering battalion on desert manoeuvres — sitting all day in an air-conditioned clinic was an improvement. But no one else there shared his equanimity.

Israel is the first country to embark on a second nationwide vaccination campaign for Covid-19. This time, the jabbing takes place on two fronts. For those over 30, who received their first two jabs at least five months ago, there’s a third “booster” dose. There’s also a push to vaccinate as many secondary pupils (over-12s) as possible before the new school year begins next Wednesday.

But although more than a million and a half Israelis have already had a third jab, the atmosphere is very different from the first roll-out, when huge vaccination centres were opened in sports stadiums and city squares, and many people, overjoyed at the prospect of lockdown lifting, broke into song and started dancing. Now, Covid cases are spiralling again — with the daily rate more than doubling in the past two weeks. Hospitalisations are also rising. “I believe we are at war,” coronavirus commissioner Professor Salman Zarka told a parliamentary committee this month. Israel is pinning its hopes on the booster programme.

It wasn’t supposed to be like this. Back in March, Israel’s vaccination programme was the envy of the world. And vaccines, which proved effective against a third wave of Covid-19 fuelled mainly by the Kent variant, allowed the country to reopen. Joyous Israelis, with the “green pass” vaccine passport on their smartphones, packed out restaurants and bars, and vaccination centres were dismantled. In March, face mask requirements were removed. Then came the Delta variant. Now, Israel finds itself serving as a test case for the longer-term efficacy of a vaccine programme.


Public health experts are not surprised. They had warned that it was impossible to predict whether the new vaccine would give adequate protection against new variants — that the protection would wane over time, perhaps in a matter of months. And that while it would probably continue to give significant protection against serious illness from Covid-19, that didn’t mean those vaccinated couldn’t still become infected and pass the virus on to others.

And that’s exactly what happened in the spring. The first Israelis to get vaccinated in December (unlike in Britain, Israel worked according to the Pfizer protocol, delivering the two doses three weeks apart) were relatively mobile and well-to-do citizens over the age of 60. As the country emerged from lockdown, many flew abroad for holidays. With the vaccine beginning to weaken, some came home infected with the Delta variant. Next, they infected their children and grandchildren, and the highly contagious strain swept through schools in the weeks before the summer holiday.

It didn’t help that around that time, the government changed and ministers took their eyes off the ball. In the spring, then prime minister Benjamin Netanyahu was basking in the success of the first roll-out, which he ascribed to his decision-making and influence with big pharma, claiming this enabled him to secure early shipments of the vaccine. Then, in May, he was distracted by the war in Gaza. Three weeks later he was out, replaced by Naftali Bennett, who sees himself as an expert on coronavirus — he ran for office partly on the basis of his manifesto, “How to Beat a Pandemic”. Bennett blithely predicted that “we can beat Covid-19 in five weeks”. That was over two months ago and Israel now has the second-highest level of new cases per capita in the world and the coronavirus wards that were closed in April have all reopened.


It isn’t all bad news, though. For a start, the vaccines are still working. After six months they are only 42 per cent effective against infection, but against serious illness they are still 80 per cent effective. Death rates are only half as high as they were in the previous waves and while less than 20 per cent of all Israeli adults have not been vaccinated, they account for half the cases in hospital. And now that the government has made the third dose available, it is already having an effect in boosting the resistance to infection of recipients.

The government decided on the boosters despite the World Health Organisation’s recommendation to wait until countries that have barely begun giving out first doses can get their vaccination campaigns under way. Israeli public health officials argue that since theirs is a small country, the booster doses do not impact on global supply, and that they are serving as a test-case for countries such as Britain which will give boosters in coming months. As the first country to administer booster jabs nationwide, Israel is embarking on a grand experiment. Bennett is adamant that the country will not enter a fourth lockdown, despite the rise in infections.


Vaccinations are so far keeping hospitals from being overwhelmed and experts are cautiously optimistic that the high uptake of third vaccines will keep it that way. For now, the school year is on track to begin next week. Face-masks are now mandatory again in all closed spaces and the target is for all secondary schools to be at least 70 per cent vaccinated before pupils return. The rest will be vaccinated at school within days of the start of term.

In primary schools, where under-12s cannot yet be vaccinated, there will be weekly testing. It’s a gamble, reopening schools while Israel is still at peak infection — experts calculate that one in every 100 Israelis is infected. And Rosh Hashanah, the Jewish New Year, a time of large family gatherings and communal prayers, begins on September 7.

However, Professor Doron Gazit, head of the Hebrew University’s Covid monitoring team, says: “We may actually have overestimated the danger of infection over the High Holidays. The chances of infection at family gatherings is counteracted by the reduced mobility as people travel less to work.”

Ultimately, the success of “containing” the Delta variant with booster jabs, face-masks and increased testing, while avoiding lockdown, could influence other governments’ policies on reopening schools and celebrating Christmas. It’s all eyes on Israel.

Newsletter

Related Articles

0:00
0:00
Close
India backs down on plan to mandate government “Sanchar Saathi” app on all smartphones
King Charles Welcomes German President Steinmeier to UK in First State Visit by Berlin in 27 Years
UK Plans Major Cutback to Jury Trials as Crown Court Backlog Nears 80,000
UK Government to Significantly Limit Jury Trials in England and Wales
U.S. and U.K. Seal Drug-Pricing Deal: Britain Agrees to Pay More, U.S. Lifts Tariffs
UK Postpones Decision Yet Again on China’s Proposed Mega-Embassy in London
Head of UK Budget Watchdog Resigns After Premature Leak of Reeves’ Budget Report
Car-sharing giant Zipcar to exit UK market by end of 2025
Reports of Widespread Drone Deployment Raise Privacy and Security Questions in the UK
UK Signals Security Concerns Over China While Pursuing Stronger Trade Links
Google warns of AI “irrationality” just as Gemini 3 launch rattles markets
Top Consultancies Freeze Starting Salaries as AI Threatens ‘Pyramid’ Model
Macron Says Washington Pressuring EU to Delay Enforcement of Digital-Regulation Probes Against Meta, TikTok and X
UK’s DragonFire Laser Downs High-Speed Drones as £316m Deal Speeds Naval Deployment
UK Chancellor Rejects Claims She Misled Public on Fiscal Outlook Ahead of Budget
Starmer Defends Autumn Budget as Finance Chief Faces Accusations of Misleading Public Finances
EU Firms Struggle with 3,000-Hour Paperwork Load — While Automakers Fear De Facto 2030 Petrol Car Ban
White House launches ‘Hall of Shame’ site to publicly condemn media outlets for alleged bias
UK Budget’s New EV Mileage Tax Undercuts Case for Plug-In Hybrids
UK Government Launches National Inquiry into ‘Grooming Gangs’ After US Warning and Rising Public Outcry
Taylor Swift Extends U.K. Chart Reign as ‘The Fate of Ophelia’ Hits Six Weeks at No. 1
250 Still Missing in the Massive Fire, 94 Killed. One Day After the Disaster: Survivor Rescued on the 16th Floor
Trump: National Guard Soldier Who Was Shot in Washington Has Died; Second Soldier Fighting for His Life
UK Chancellor Reeves Defends Tax Rises as Essential to Reduce Child Poverty and Stabilise Public Finances
No Evidence Found for Claim That UK Schools Are Shifting to Teaching American English
European Powers Urge Israel to Halt West Bank Settler Violence Amid Surge in Attacks
"I Would Have Given Her a Kidney": She Lent Bezos’s Ex-Wife $1,000 — and Received Millions in Return
European States Approve First-ever Military-Grade Surveillance Network via ESA
UK to Slash Key Pension Tax Perk, Targeting High Earners Under New Budget
UK Government Announces £150 Annual Cut to Household Energy Bills Through Levy Reforms
UK Court Hears Challenge to Ban on Palestine Action as Critics Decry Heavy-Handed Measures
Investors Rush Into UK Gilts and Sterling After Budget Eases Fiscal Concerns
UK to Raise Online Betting Taxes by £1.1 Billion Under New Budget — Firms Warn of Fallout
Lamine Yamal? The ‘Heir to Messi’ Lost to Barcelona — and the Kingdom Is in a Frenzy
Warner Music Group Drops Suit Against Suno, Launches Licensed AI-Music Deal
HP to Cut up to 6,000 Jobs Globally as It Ramps Up AI Integration
MediaWorld Sold iPad Air for €15 — Then Asked Customers to Return Them or Pay More
UK Prime Minister Sir Keir Starmer Promises ‘Full-Time’ Education for All Children as School Attendance Slips
UK Extends Sugar Tax to Sweetened Milkshakes and Lattes in 2028 Health Push
UK Government Backs £49 Billion Plan for Heathrow Third Runway and Expansion
UK Gambling Firms Report £1bn Surge in Annual Profits as Pressure Mounts for Higher Betting Taxes
UK Shares Advance Ahead of Budget as Financials and Consumer Staples Lead Gains
Domino’s UK CEO Andrew Rennie Steps Down Amid Strategic Reset
UK Economy Stalls as Reeves Faces First Budget Test
UK Economy’s Weak Start Adds Pressure on Prime Minister Starmer
UK Government Acknowledges Billionaire Exodus Amid Tax Rise Concerns
UK Budget 2025: Markets Brace as Chancellor Faces Fiscal Tightrope
UK Unveils Strategic Plan to Secure Critical Mineral Supply Chains
UK Taskforce Calls for Radical Reset of Nuclear Regulation to Cut Costs and Accelerate Build
UK Government Launches Consultation on Major Overhaul of Settlement Rules
×