London Daily

Focus on the big picture.
Tuesday, Nov 25, 2025

How did coronavirus start and where did it come from? Was it really Wuhan's animal market?

How did coronavirus start and where did it come from? Was it really Wuhan's animal market?

It’s likely Covid-19 originated in bats, scientists say. But did it then spread to pangolins and humans?
In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal.

The rest is part of an awful history still in the making, with Covid-19 spreading from that first cluster in the capital of China’s Hubei province to a pandemic that has killed about 80,000 people so far.

Stock footage of pangolins – a scaly mammal that looks like an anteater – have made it on to news bulletins, suggesting this animal was the staging post for the virus before it spread to humans.

But there is uncertainty about several aspects of the Covid-19 origin story that scientists are trying hard to unravel, including which species passed it to a human. They’re trying hard because knowing how a pandemic starts is a key to stopping the next one.

Prof Stephen Turner, head of the department of microbiology at Melbourne’s Monash University, says what’s most likely is that virus originated in bats.

But that’s where his certainty ends, he says.

On the hypothesis that the virus emerged at the Wuhan live animal market from an interaction between an animal and a human, Turner says: “I don’t think it’s conclusive by any means.”

“Part of the problem is that the information is only as good as the surveillance,” he says, adding that viruses of this type are circulating all the time in the animal kingdom.

The fact that the virus has infected a tiger in a New York zoo shows how viruses can move around between species, he says. “Understanding the breadth of species this virus can infect is important as it helps us narrow down down where it might have come from.”

Scientists say it is highly likely that the virus came from bats but first passed through an intermediary animal in the same way that another coronavirus – the 2002 Sars outbreak – moved from horseshoe bats to cat-like civets before infecting humans.

One animal implicated as an intermediary host between bats and humans is the pangolin. The International Union for Conservation of Nature says they are “the most illegally traded mammal in the world” and are prized for their meat and the claimed medicinal properties of their scales.

As reported in Nature, pangolins were not listed on the inventory of items being sold in Wuhan, although this omission could be deliberate as it’s illegal to sell them.

“Whether the poor pangolin was the species at which it jumped, it’s not clear,” Turner says. “It’s either mixed in something else, mixed in a poor pangolin, or it’s jumped into people and evolved in people.”

Prof Edward Holmes, of the University of Sydney, was a co-author on a Nature study that examined the likely origins of the virus by looking at its genome. On social media he has stressed that the identity of the species that served as an intermediate host for the virus is “still uncertain”.

One statistical study looked at a characteristic of the virus that evolved to enable it to latch on to human cells. Pangolins were able to develop this characteristic, but so were cats, buffalo, cattle, goats, sheep and pigeons.

Another study claimed to have ruled out pangolins as an intermediary altogether, because samples of similar viruses taken from pangolins lacked a chain of amino acids seen in the virus now circulating in humans.

The study Holmes worked on suggested that the scenario in which a human at the Wuhan market interacted with an animal that carried the virus was only one potential version of the Covid-19 origin story. Another was the possibility that a descendent of the virus jumped into humans and then adapted as it was passed from human to human.

“Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases to trigger the surveillance system that detected it,” the study said.

Analysis of the first 41 Covid-19 patients in medical journal the Lancet found that 27 of them had direct exposure to the Wuhan market. But the same analysis found that the first known case of the illness did not.

This might be another reason to doubt the established story.

Prof Stanley Perlman, a leading immunologist at the University of Iowa and an expert on previous coronavirus outbreaks that have stemmed from animals, says the idea the link to the Wuhan market is coincidental “cannot be ruled out” but that possibility “seems less likely” because the genetic material of the virus had been found in the market environment.

Perlman told Guardian Australia he does believe there was an intermediary animal but adds that while pangolins are possible candidates, they “are not proven to be the key intermediary”.

“I suspect that any evolution [of the virus] occurred in the intermediate animal if there was one. There has been no substantial changes in the virus in the three months of the pandemic, indicating that the virus is well adapted to humans.”

So-called wet markets – where live animals are traded – have been implicated in previous outbreaks of coronaviruses, in particular Sars.

Dr Michelle Baker, an immunologist at CSIRO who studies viruses in bats, says some of the research on Covid-19’s origins have stepped off from what was known from the past.

But “we really don’t know” how accurate the origin story is, she says: “There’s some sort of connection [to the Wuhan market] and there were people exposed to the market that were infected.”

Baker says what is “very likely” is that the virus originated in a bat. “It’s a likely scenario but we will never know. The market was cleaned up quite quickly. We can only speculate.”

“These wet markets have been identified as an issue because you do have species interacting,” she says. “It’s an opportunity to highlight the dangers of them and an opportunity to clamp down on them.”

Turner adds: “We’ve found the ancestors of the virus, but having broader knowledge of the coronavirus in other species might give us a hint about the evolution of this thing and how it jumped.”
Newsletter

Related Articles

0:00
0:00
Close
UK Economy Stalls as Reeves Faces First Budget Test
UK Economy’s Weak Start Adds Pressure on Prime Minister Starmer
UK Government Acknowledges Billionaire Exodus Amid Tax Rise Concerns
UK Budget 2025: Markets Brace as Chancellor Faces Fiscal Tightrope
UK Unveils Strategic Plan to Secure Critical Mineral Supply Chains
UK Taskforce Calls for Radical Reset of Nuclear Regulation to Cut Costs and Accelerate Build
UK Government Launches Consultation on Major Overhaul of Settlement Rules
Google Struggles to Meet AI Demand as Infrastructure, Energy and Supply-Chain Gaps Deepen
Car Parts Leader Warns Europe Faces Heavy Job Losses in ‘Darwinian’ Auto Shake-Out
Arsenal Move Six Points Clear After Eze’s Historic Hat-Trick in Derby Rout
Wealthy New Yorkers Weigh Second Homes as the ‘Mamdani Effect’ Ripples Through Luxury Markets
Families Accuse OpenAI of Enabling ‘AI-Driven Delusions’ After Multiple Suicides
UK Unveils Critical-Minerals Strategy to Break China Supply-Chain Grip
Taylor Swift’s “The Fate of Ophelia” Extends U.K. No. 1 Run to Five Weeks
UK VPN Sign-Ups Surge by Over 1,400 % as Age-Verification Law Takes Effect
Former MEP Nathan Gill Jailed for Over Ten Years After Taking Pro-Russia Bribes
Majority of UK Entrepreneurs Regard Government as ‘Anti-Business’, Survey Shows
UK’s Starmer and US President Trump Align as Geneva Talks Probe Ukraine Peace Plan
UK Prime Minister Signals Former Prince Andrew Should Testify to US Epstein Inquiry
Royal Navy Deploys HMS Severn to Shadow Russian Corvette and Tanker Off UK Coast
China’s Wedding Boom: Nightclubs, Mountains and a Demographic Reset
Fugees Founding Member Pras Michel Sentenced to 14 Years in High-Profile US Foreign Influence Case
WhatsApp’s Unexpected Rise Reshapes American Messaging Habits
United States: Judge Dressed Up as Elvis During Hearings – and Was Forced to Resign
Johnson Blasts ‘Incoherent’ Covid Inquiry Findings Amid Report’s Harsh Critique of His Government
Lord Rothermere Secures £500 Million Deal to Acquire Telegraph Titles
Maduro Tightens Security Measures as U.S. Strike Threat Intensifies
U.S. Envoys Deliver Ultimatum to Ukraine: Sign Peace Deal by Thursday or Risk Losing American Support
Zelenskyy Signals Progress Toward Ending the War: ‘One of the Hardest Moments in History’ (end of his business model?)
U.S. Issues Alert Declaring Venezuelan Airspace a Hazard Due to Escalating Security Conditions
The U.S. State Department Announces That Mass Migration Constitutes an Existential Threat to Western Civilization and Undermines the Stability of Key American Allies
Students Challenge AI-Driven Teaching at University of Staffordshire
Pikeville Medical Center Partners with UK’s Golisano Children’s Network to Expand Pediatric Care
Germany, France and UK Confirm Full Support for Ukraine in US-Backed Security Plan
UK Low-Traffic Neighbourhoods Face Rising Backlash as Pandemic Schemes Unravel
UK Records Coldest Night of Autumn as Sub-Zero Conditions Sweep the Country
UK at Risk of Losing International Doctors as Workforce Exodus Grows, Regulator Warns
ASU Launches ASU London, Extending Its Innovation Brand to the UK Education Market
UK Prime Minister Keir Starmer to Visit China in January as Diplomatic Reset Accelerates
Google Launches Voluntary Buyouts for UK Staff Amid AI-Driven Company Realignment
UK braces for freezing snap as snow and ice warnings escalate
Majority of UK Novelists Fear AI Could Displace Their Work, Cambridge Study Finds
UK's Carrier Strike Group Achieves Full Operational Capability During NATO Drill in Mediterranean
Trump and Mamdani to Meet at the White House: “The Communist Asked”
Nvidia Again Beats Forecasts, Shares Jump in After-Hours Trading
Wintry Conditions Persist Along UK Coasts After Up to Seven Centimetres of Snow
UK Inflation Eases to 3.6 % in October, Opening Door for Rate Cut
UK Accelerates Munitions Factory Build-Out to Reinforce Warfighting Readiness
UK Consumer Optimism Plunges Ahead of November Budget
A Decade of Innovation Stagnation at Apple: The Cook Era Critique
×