London Daily

Focus on the big picture.
Saturday, Dec 20, 2025

How did coronavirus start and where did it come from? Was it really Wuhan's animal market?

How did coronavirus start and where did it come from? Was it really Wuhan's animal market?

It’s likely Covid-19 originated in bats, scientists say. But did it then spread to pangolins and humans?
In the public mind, the origin story of coronavirus seems well fixed: in late 2019 someone at the now world-famous Huanan seafood market in Wuhan was infected with a virus from an animal.

The rest is part of an awful history still in the making, with Covid-19 spreading from that first cluster in the capital of China’s Hubei province to a pandemic that has killed about 80,000 people so far.

Stock footage of pangolins – a scaly mammal that looks like an anteater – have made it on to news bulletins, suggesting this animal was the staging post for the virus before it spread to humans.

But there is uncertainty about several aspects of the Covid-19 origin story that scientists are trying hard to unravel, including which species passed it to a human. They’re trying hard because knowing how a pandemic starts is a key to stopping the next one.

Prof Stephen Turner, head of the department of microbiology at Melbourne’s Monash University, says what’s most likely is that virus originated in bats.

But that’s where his certainty ends, he says.

On the hypothesis that the virus emerged at the Wuhan live animal market from an interaction between an animal and a human, Turner says: “I don’t think it’s conclusive by any means.”

“Part of the problem is that the information is only as good as the surveillance,” he says, adding that viruses of this type are circulating all the time in the animal kingdom.

The fact that the virus has infected a tiger in a New York zoo shows how viruses can move around between species, he says. “Understanding the breadth of species this virus can infect is important as it helps us narrow down down where it might have come from.”

Scientists say it is highly likely that the virus came from bats but first passed through an intermediary animal in the same way that another coronavirus – the 2002 Sars outbreak – moved from horseshoe bats to cat-like civets before infecting humans.

One animal implicated as an intermediary host between bats and humans is the pangolin. The International Union for Conservation of Nature says they are “the most illegally traded mammal in the world” and are prized for their meat and the claimed medicinal properties of their scales.

As reported in Nature, pangolins were not listed on the inventory of items being sold in Wuhan, although this omission could be deliberate as it’s illegal to sell them.

“Whether the poor pangolin was the species at which it jumped, it’s not clear,” Turner says. “It’s either mixed in something else, mixed in a poor pangolin, or it’s jumped into people and evolved in people.”

Prof Edward Holmes, of the University of Sydney, was a co-author on a Nature study that examined the likely origins of the virus by looking at its genome. On social media he has stressed that the identity of the species that served as an intermediate host for the virus is “still uncertain”.

One statistical study looked at a characteristic of the virus that evolved to enable it to latch on to human cells. Pangolins were able to develop this characteristic, but so were cats, buffalo, cattle, goats, sheep and pigeons.

Another study claimed to have ruled out pangolins as an intermediary altogether, because samples of similar viruses taken from pangolins lacked a chain of amino acids seen in the virus now circulating in humans.

The study Holmes worked on suggested that the scenario in which a human at the Wuhan market interacted with an animal that carried the virus was only one potential version of the Covid-19 origin story. Another was the possibility that a descendent of the virus jumped into humans and then adapted as it was passed from human to human.

“Once acquired, these adaptations would enable the pandemic to take off and produce a sufficiently large cluster of cases to trigger the surveillance system that detected it,” the study said.

Analysis of the first 41 Covid-19 patients in medical journal the Lancet found that 27 of them had direct exposure to the Wuhan market. But the same analysis found that the first known case of the illness did not.

This might be another reason to doubt the established story.

Prof Stanley Perlman, a leading immunologist at the University of Iowa and an expert on previous coronavirus outbreaks that have stemmed from animals, says the idea the link to the Wuhan market is coincidental “cannot be ruled out” but that possibility “seems less likely” because the genetic material of the virus had been found in the market environment.

Perlman told Guardian Australia he does believe there was an intermediary animal but adds that while pangolins are possible candidates, they “are not proven to be the key intermediary”.

“I suspect that any evolution [of the virus] occurred in the intermediate animal if there was one. There has been no substantial changes in the virus in the three months of the pandemic, indicating that the virus is well adapted to humans.”

So-called wet markets – where live animals are traded – have been implicated in previous outbreaks of coronaviruses, in particular Sars.

Dr Michelle Baker, an immunologist at CSIRO who studies viruses in bats, says some of the research on Covid-19’s origins have stepped off from what was known from the past.

But “we really don’t know” how accurate the origin story is, she says: “There’s some sort of connection [to the Wuhan market] and there were people exposed to the market that were infected.”

Baker says what is “very likely” is that the virus originated in a bat. “It’s a likely scenario but we will never know. The market was cleaned up quite quickly. We can only speculate.”

“These wet markets have been identified as an issue because you do have species interacting,” she says. “It’s an opportunity to highlight the dangers of them and an opportunity to clamp down on them.”

Turner adds: “We’ve found the ancestors of the virus, but having broader knowledge of the coronavirus in other species might give us a hint about the evolution of this thing and how it jumped.”
Newsletter

Related Articles

0:00
0:00
Close
Scambodia: The World Owes Thailand’s Military a Profound Debt of Gratitude
Women in Partial Nudity — and Bill Clinton in a Dress and Heels: The Images Revealed in the “Epstein Files”
US Envoy Witkoff to Convene Security Advisers from Ukraine, UK, France and Germany in Miami as Peace Efforts Intensify
UK Retailers Report Sharp Pre-Christmas Sales Decline and Weak Outlook, CBI Survey Shows
UK Government Rejects Use of Frozen Russian Assets to Fund Aid for Ukraine
UK Financial Conduct Authority Opens Formal Investigation into WH Smith After Accounting Errors
UK Issues Final Ultimatum to Roman Abramovich Over £2.5bn Chelsea Sale Funds for Ukraine
Rare Pink Fog Sweeps Across Parts of the UK as Met Office Warns of Poor Visibility
UK Police Pledge ‘More Assertive’ Enforcement to Tackle Antisemitism at Protests
UK Police Warn They Will Arrest Protesters Chanting ‘Globalise the Intifada’
Trump Files $10 Billion Defamation Lawsuit Against BBC as Broadcaster Pledges Legal Defence
UK Says U.S. Tech Deal Talks Still Active Despite Washington’s Suspension of Prosperity Pact
UK Mortgage Rules to Give Greater Flexibility to Borrowers With Irregular Incomes
UK Treasury Moves to Position Britain as Leading Global Hub for Crypto Firms
U.S. Freezes £31 Billion Tech Prosperity Deal With Britain Amid Trade Dispute
Prince Harry and Meghan’s Potential UK Return Gains New Momentum Amid Security Review and Royal Dialogue
Zelensky Opens High-Stakes Peace Talks in Berlin with Trump Envoy and European Leaders
Historical Reflections on Press Freedom Emerge Amid Debate Over Trump’s Media Policies
UK Boosts Protection for Jewish Communities After Sydney Hanukkah Attack
UK Government Declines to Comment After ICC Prosecutor Alleges Britain Threatened to Defund Court Over Israel Arrest Warrant
Apple Shutters All Retail Stores in the United Kingdom Under New National COVID-19 Lockdown
US–UK Technology Partnership Strains as Key Trade Disagreements Emerge
UK Police Confirm No Further Action Over Allegation That Andrew Asked Bodyguard to Investigate Virginia Giuffre
Giuffre Family Expresses Deep Disappointment as UK Police Decline New Inquiry Into Andrew Mountbatten-Windsor Claims
Transatlantic Trade Ambitions Hit a Snag as UK–US Deal Faces Emerging Challenges
Ex-ICC Prosecutor Alleges UK Threatened to Withdraw Funding Over Netanyahu Arrest Warrant Bid
UK Disciplinary Tribunal Clears Carter-Ruck Lawyer of Misconduct in OneCoin Case
‘Pink Ladies’ Emerge as Prominent Face of UK Anti-Immigration Protests
Nigel Farage Says Reform UK Has Become Britain’s Largest Party as Labour Membership Falls Sharply
Google DeepMind and UK Government Launch First Automated AI Lab to Accelerate Scientific Discovery
UK Economy Falters Ahead of Budget as Growth Contracts and Confidence Wanes
Australia Approves Increased Foreign Stake in Strategic Defence Shipbuilder
Former UK Prime Minister Boris Johnson proclaims, “For Ukraine, surrendering their land would be a nightmare.”
Microsoft Challenges £2.1 Billion UK Cloud Licensing Lawsuit at Competition Tribunal
Fake Doctor in Uttar Pradesh Accused of Killing Woman After Performing YouTube-Based Surgery
Hackers Are Hiding Malware in Open-Source Tools and IDE Extensions
Traveling to USA? Homeland Security moving toward requiring foreign travelers to share social media history
UK Officials Push Back at Trump Saying European Leaders ‘Talk Too Much’ About Ukraine
UK Warns of Escalating Cyber Assault Linked to Putin’s State-Backed Operations
UK Consumer Spending Falters in November as Households Hold Back Ahead of Budget
UK Orders Fresh Review of Prince Harry’s Security Status After Formal Request
U.S. Authorises Nvidia to Sell H200 AI Chips to China Under Security Controls
Trump in Direct Assault: European Leaders Are Weak, Immigration a Disaster. Russia Is Strong and Big — and Will Win
"App recommendation" or disguised advertisement? ChatGPT Premium users are furious
"The Great Filtering": Australia Blocks Hundreds of Thousands of Minors From Social Networks
Mark Zuckerberg Pulls Back From Metaverse After $70 Billion Loss as Meta Shifts Priorities to AI
Nvidia CEO Says U.S. Data-Center Builds Take Years while China ‘Builds a Hospital in a Weekend’
Indian Airports in Turmoil as IndiGo Cancels Over a Thousand Flights, Stranding Thousands
Hollywood Industry on Edge as Netflix Secures Near-$60 Bln Loan for Warner Bros Takeover
Drugs and Assassinations: The Connection Between the Italian Mafia and Football Ultras
×