London Daily

Focus on the big picture.
Tuesday, Feb 24, 2026

3 Reasons A Negative Test Doesn't Necessarily Mean You're Not Infected

3 Reasons A Negative Test Doesn't Necessarily Mean You're Not Infected

Nasopharyngeal swabs, which collect samples from the back of your nose and throat, are still more reliable than less invasive throat swabs and nasal swabs.

Rampant community transmission of the coronavirus and a crippled vaccine rollout have boxed people into a corner: Many are relying on negative test results, inherently limited in usefulness, as a certificate of clearance to see family and friends.

While testing is critical to containing the outbreak, a negative test result is not a free pass to forgo social distancing, mask-wearing and large gatherings. Here are a few reminders about what a negative coronavirus test means and doesn't mean.

The tests still have varying degrees of accuracy


Coronavirus testing in the United States has ramped up significantly in recent months, with the daily test count hovering around 1.5 million in January. There are two categories of tests: PCR (polymerase chain reaction) tests - considered the "gold standard" - and less-accurate antigen tests.

PCR tests use a molecular process and are processed in a lab. Faster and cheaper antigen tests detect proteins on the virus's surface. Most rapid home tests, estimated to be about 90% accurate, use the antigen technology.

PCR tests are your best bet for getting a sense of whether you're infected, even though those results take longer than antigen results. Still, PCR tests can result in false negatives.

That's in part because the giant cotton swabs used in many of those tests may not pick up all traces of the virus deep in your nasal cavity. The virus may have moved from your nose to your lungs or somewhere else, or the swab may not have been inserted far enough.

But nasopharyngeal swabs, which collect samples from the back of your nose and throat, are still more reliable than less invasive throat swabs and nasal swabs.

A test may not be able to detect the virus early in its course


Early in an infection, the virus may not have reproduced enough to be detectable. The false negative rate of PCR tests on the day of exposure is 100%, but falls to about 38% five days later as symptoms usually set in, according to an analysis published in the Annals of Internal Medicine. The rate decreases further, to about 20%, after three more days.

"We don't yet understand exactly when a person who's infected will start testing positive for the virus," Muge Cevik, a clinical lecturer in infectious diseases and medical virology at the University of St. Andrews, told The Washington Post in December. "So there are situations when a person could test negative, but they could still be contagious."

If you think you've been exposed to the coronavirus but receive a negative test result, you may want to get tested again in a few days. You should also self-quarantine while you're waiting for results.

The Centers for Disease Control and Prevention suggests quarantining for 14 days but considers 10 days acceptable if you haven't experienced symptoms. The agency also says it's probably safe to leave your home after seven days if you have no symptoms and have received a negative test result.

You could test negative and become infected soon afterward


On top of the other limitations, a coronavirus test captures just one moment in time. You could walk out of a testing center and immediately contract the virus. The test you just took is not going to reflect your new infection.

This constraint is particularly important to keep in mind if you plan to travel after you learn the outcome of your test. A crowded airport terminal or rest-stop restroom could expose you to the virus after you've concluded that a negative test means you're not infected.

Gathering indoors is inherently risky, and a negative test result doesn't tell the full story.

Newsletter

Related Articles

0:00
0:00
Close
Lord Mandelson Condemns Arrest as Driven by ‘Baseless Suggestion’ He Would Flee Abroad
Former UK Ambassador Released on Bail Following Arrest in Epstein-Linked Investigation
UK Parliament Orders Release of Former Prince Andrew’s Government Vetting Files
Reddit Fined £14 Million by UK Regulator Over Failures in Age Verification Controls
UK Moves to Tighten Regulation of Netflix, Disney+ and Prime Video Under New Media Rules
UK Sanctions New Zealand Insurer Maritime Mutual Following Allegations Over Russian Oil Cover
Reform MP Danny Kruger Condemns UK’s ‘Unregulated Sexual Economy’ in Call for Tougher Controls
UK Sanctions Russian ‘Illicit Oil Traders’ After Email Blunder Exposes Sanctions Evasion Network
Russia Amplifies Baseless Claims That UK and France Plan to Arm Ukraine with Nuclear Weapons
UK Imposes Sanctions on Two Georgian Television Channels Over Alleged Russian Disinformation
United States National Parks See Noticeable Drop in Visitors from Canada, U.K. and Australia
UK, Australia, Canada and New Zealand Escalate Sanctions on Russia as Ukraine War Marks Four Years
I Gave Andrew a Nude Massage Inside Buckingham Palace
UK Economy Faces Acute Strain as Trump’s Global Tariff Reshapes Trade Landscape
UK Signals Retaliation Is Possible as New US Tariff Policy Threatens Trade Stability
British Police Arrest Former Ambassador Peter Mandelson in Epstein-Related Misconduct Probe
Australia Officially Supports Proposal to Remove Andrew Mountbatten-Windsor from Royal Succession
Victorian Premier Jacinta Allan remains silent on ISIS brides' resettlement plans in Melbourne
Former UK Ambassador Peter Mandelson Arrested in Connection with Jeffrey Epstein
Jacob Rees Mogg afraid to talk about Peter Mandelson arrest on “suspicion of misconduct in a public office” (Pedophilia, corruption, etc.)
United Nations Calls for Global Action Against Disinformation and Hate Speech Online
Tucker Carlson warns of an inevitable clash in Western societies over mass migration
President Trump warns countries against abandoning recent trade deals with the US
Diverging Polls Show Mixed Signals on UK Economic Revival as Confidence Remains Fragile
Spotify Expands AI-Driven ‘Prompted Playlists’ Feature to the United Kingdom and Other Markets
Greens and Reform UK Surge in Manchester By-Election, Threatening Labour’s Historic Stronghold
UK Businesses Push for Closer European Trade Links Amid Renewed US Tariff Uncertainty
Deloitte Global Overhaul Sparks Leadership Contest in the United Kingdom
University of Kentucky and Microsoft to Showcase Campus-Wide AI Innovation
UK Food System Faces Acute Vulnerability to Shocks, Experts Warn
Reform UK’s Proposed ICE-Style Deportation Scheme Triggers Sharp Backlash
U.S. Global Tariff Push Leaves Britain, Australia and Others Facing Higher Costs and Trade Strain
UK Police Officers Guarded 2010 Epstein Dinner Attended by Prince Andrew, Reports Say
US Trade Representative Affirms Commitment to Existing Tariff Agreements with UK and Other Partners
Activists at the Louvre hung a framed Reuters photograph of Andrew Mountbatten-Windsor slumped in the back of a car leaving a police station on the day of his arrest
The royal biographer said that he expected the police to 'look at the money trail' - including Sarah Ferguson borrowing money from Epstein
A Protestor screams in NYC: “Bill Gates is on the Epstein’s List…”
FBI and Secret Service Hold Press Conference After Shooting Incident at Mar-a-Lago
Mark Zuckerberg Testifies in Trial Over Social Media's Impact on Children's Mental Health
Maggie Oliver exposes Keir Starmer using letters to close child rapists investigations
Kouri Richie's wrote a children’s book to help her sons grieve the death of their father. Now she’ll stand trial for his murder
New York Braces for Major Snowstorm With Up to 18 Inches Forecast and Blizzard Warnings Issued
Mexican Military Kills CJNG Leader Nemesio Oseguera Cervantes as Violence Erupts Across Jalisco
Metropolitan Police Deploys Palantir-Powered AI to Flag Potential Officer Misconduct
UK Parliament Rebukes Police Over Ban on Israeli Football Fans
Britain Emerges Among a Small Group of Nations Without a Religious Majority
UK’s Manufacturing Base at Risk as Soaring Energy Costs Weigh on Industry
Matt Goodwin’s Unconventional Campaign for Reform UK in the Gorton and Denton By-Election
US Military Movements in the UK Spark Speculation Over Preparations Related to Iran Tensions
UK Faces Significant Economic Risk From Trump’s New Global Tariff Regime
×