London Daily

Focus on the big picture.
Wednesday, Jun 24, 2026

3 Reasons A Negative Test Doesn't Necessarily Mean You're Not Infected

3 Reasons A Negative Test Doesn't Necessarily Mean You're Not Infected

Nasopharyngeal swabs, which collect samples from the back of your nose and throat, are still more reliable than less invasive throat swabs and nasal swabs.

Rampant community transmission of the coronavirus and a crippled vaccine rollout have boxed people into a corner: Many are relying on negative test results, inherently limited in usefulness, as a certificate of clearance to see family and friends.

While testing is critical to containing the outbreak, a negative test result is not a free pass to forgo social distancing, mask-wearing and large gatherings. Here are a few reminders about what a negative coronavirus test means and doesn't mean.

The tests still have varying degrees of accuracy


Coronavirus testing in the United States has ramped up significantly in recent months, with the daily test count hovering around 1.5 million in January. There are two categories of tests: PCR (polymerase chain reaction) tests - considered the "gold standard" - and less-accurate antigen tests.

PCR tests use a molecular process and are processed in a lab. Faster and cheaper antigen tests detect proteins on the virus's surface. Most rapid home tests, estimated to be about 90% accurate, use the antigen technology.

PCR tests are your best bet for getting a sense of whether you're infected, even though those results take longer than antigen results. Still, PCR tests can result in false negatives.

That's in part because the giant cotton swabs used in many of those tests may not pick up all traces of the virus deep in your nasal cavity. The virus may have moved from your nose to your lungs or somewhere else, or the swab may not have been inserted far enough.

But nasopharyngeal swabs, which collect samples from the back of your nose and throat, are still more reliable than less invasive throat swabs and nasal swabs.

A test may not be able to detect the virus early in its course


Early in an infection, the virus may not have reproduced enough to be detectable. The false negative rate of PCR tests on the day of exposure is 100%, but falls to about 38% five days later as symptoms usually set in, according to an analysis published in the Annals of Internal Medicine. The rate decreases further, to about 20%, after three more days.

"We don't yet understand exactly when a person who's infected will start testing positive for the virus," Muge Cevik, a clinical lecturer in infectious diseases and medical virology at the University of St. Andrews, told The Washington Post in December. "So there are situations when a person could test negative, but they could still be contagious."

If you think you've been exposed to the coronavirus but receive a negative test result, you may want to get tested again in a few days. You should also self-quarantine while you're waiting for results.

The Centers for Disease Control and Prevention suggests quarantining for 14 days but considers 10 days acceptable if you haven't experienced symptoms. The agency also says it's probably safe to leave your home after seven days if you have no symptoms and have received a negative test result.

You could test negative and become infected soon afterward


On top of the other limitations, a coronavirus test captures just one moment in time. You could walk out of a testing center and immediately contract the virus. The test you just took is not going to reflect your new infection.

This constraint is particularly important to keep in mind if you plan to travel after you learn the outcome of your test. A crowded airport terminal or rest-stop restroom could expose you to the virus after you've concluded that a negative test means you're not infected.

Gathering indoors is inherently risky, and a negative test result doesn't tell the full story.

Newsletter

Related Articles

0:00
0:00
Close
UK Biotechnology Sector Receives Increased Public Funding to Support Regional Growth
Police Chiefs Update National Protest Management Guidelines Amid Rising Demonstration Activity
UK Aviation Regulator Expands Support for Regional Airports to Strengthen Domestic Routes
CMA Launches Investigation Into Retail Pricing Across UK Grocery Sector
UK Energy Operator Warns of Winter Supply Pressures Despite Stable Overall Grid Outlook
UK Research Council Expands Funding for Regional Biotechnology and Life Sciences Clusters
UK Compensation Scheme for Post Office Horizon Scandal Reaches 80 Percent Completion
Police Chiefs Issue Updated National Guidance on Managing Large Public Demonstrations
UK Expands Regional Airport Funding Scheme to Boost Domestic Connectivity
UK Competition Watchdog Launches Inquiry Into Grocery Pricing Practices
National Grid Warns of Tight Energy Management Needs During Upcoming Winter Peak Demand
UK Education Department Introduces National Standards for AI Use in Secondary Schools
UK High Court Clears North Sea Carbon Capture Project After Final Legal Challenge Fails
Northern Ireland Leaders Hold Emergency Talks on Trade Disruption Under Windsor Framework
Welsh Government Moves to Expand Social Housing in Response to Severe Affordability Pressures
UK Economy Sees Unexpected Rise in Business Investment in Second Quarter, ONS Data Shows
Scottish Government Unveils Multi-Billion Pound Investment Plan for Renewable Energy and Grid Expansion
UK and EU Agree Enhanced Defence Cooperation Pact Covering Intelligence and North Sea Security
Prime Minister Orders Independent Review of NHS Performance After Record Waiting Lists
Bank of England Holds Interest Rates at 5 Percent as Services Inflation Remains Persistent
UK Heatwave Disrupts Transport, Healthcare and Public Services as Red Weather Alerts Expand Nationwide
Barclays Warns of Growing Cyber Risk Divide Between Large UK Firms and Micro Businesses
European Defence Plans Including Ukraine Integration Prompt UK Strategic Reassessment
UK Equity Markets React as US–Iran Peace Roadmap Eases Oil Price Pressures
United Kingdom Expands Global Clean Energy Partnerships With Brazil, Morocco and Tanzania
Lord David Frost Urges Incoming UK Leadership to Abandon EU Regulatory Reset Strategy
Housing Groups Support Amendment to Strengthen Fire and Gas Safety Access Powers in Social Housing
South London NHS Estates Staff Ballot on Industrial Action Over Pay Structures in Hospital Maintenance Services
United Kingdom Government Invests £60 Million in AI Research Labs at Oxford and University College London
Barclays Cyber Security Report Highlights Rising Threat Exposure Among UK Small Businesses in AI-Driven Attacks
UK Met Office Heatwave Triggers Transport Warnings as Rail Operators Urge Cancellations Amid Infrastructure Strain
South London NHS Estates Workers Ballot for Strike Action Over Pay Disputes Across Major London Hospitals
Barclays Warns of Severe Cyber Security Gap Between Large Corporations and Small Businesses in the United Kingdom
United Kingdom Government Allocates £60 Million for Artificial Intelligence Research Laboratories at Oxford and UCL
National Health Service Approves Teplizumab Treatment to Delay Onset of Type One Diabetes in First European Rollout
Met Office Issues Rare Red Extreme Heat Warning Across London, South East and West Midlands as Transport and Health Systems Face Disruption
Prime Minister Keir Starmer Resigns After Labour Party Revolt Following Economic Stagnation and Local Election Losses
United Kingdom Economy Contracts for Second Consecutive Month as Private Sector Weakens and Job Loss Fears Rise
Taxpayer Support Grows for Higher Digital Levies on Multinational Tech Companies
Bank of England Signals Caution Over Inflation Despite Easing Energy Prices
Lloyds Banking Group Expands Artificial Intelligence Hiring Amid Sector-Wide Automation Shift
Film Producer Corporate Collapse Leaves Creditors Facing Unrecoverable Losses
UK Ten-Year Brexit Anniversary Highlights Ongoing Political and Economic Uncertainty
Nottingham Maternity Scandal Inquiry Reveals Systemic Failings in NHS Care
Met Office Heatwave Prompts Public Health Warnings Across United Kingdom
Concerns Rise Over Fiscal Stability as Political Uncertainty Weighs on UK Borrowing Costs
UK Taxpayers Back Higher Digital Taxes on Global Technology Firms, Survey Shows
Bank of England Holds Interest Rates Steady Amid Persistent Services Inflation
Reform UK and Opposition Leaders Call for General Election Following Starmer’s Departure
Ten Years After Brexit Referendum, UK Faces Ongoing Political Fragmentation and Economic Debate
×