The Red Devils sealed their place in the quarter-finals with a 2-0 win against the Clarets at Old Trafford.
It was United’s first game back since the World Cup started after a 38-day break for the tournament in Qatar.
The likes of Rashford, Fernandes and Casemiro all competed in the middle-east until the quarter-final stage but they started at Old Trafford against Kompany’s side.
Christian Eriksen put United ahead in the first half when he converted Aaron Wan-Bissaka’s cross, who was slipped in thanks to a fantastic pass from Fernandes.
Rashford then doubled the lead in the second half with a sensational 65-yard run from his own half, which ended with him striking a powerful effort into the bottom corner.
Burnley had plenty of chances of their own but the attacking prowess of United was enough to put Erik ten Hag’s side through.
And Kompany admitted afterwards that Fernandes and Rashford were the difference-makers.