Goldman Sachs reviews role in Chinese tech firm Megvii
US imposes China visa restrictions over Uighur issue
Human rights groups and the UN say China has rounded up and detained more than a million Uighurs and other mostly Muslim minorities in detention camps.
China insists they're "vocational training centres" aimed at preventing terrorism, promoting integration into Chinese society and providing employment.
The US and China have been locked in a long-running trade spat over a variety of thorny issues.
The US has been demanding better protection for US intellectual property, and an end to both cyber theft and the forced transfer of technology to Chinese firms.
It also wants China to reduce industrial subsidies and improve access to Chinese markets to US companies.
These talks are the first minister-level negotiations in more than two months.
Many trade experts have low expectations for the talks, suggesting an interim deal might be possible, while a major agreement is unlikely.
"I think both sides have an impetus to get to that table. The question is whether there can be a mini-deal that comes out of it. Certainly nothing comprehensive," said Sherry Madera, a former Minister-Counsellor at the British Embassy in Beijing.
Former Deputy Assistant US Trade Representative Matt Gold said that if the talks went well, China might make additional agricultural purchases and the US might push back its planned tariff hike.
But he said neither Chinese President Xi Jinping nor US President Donald Trump seem to think ending their trade dispute is urgent.
For Mr Trump, it is an issue he can use in the upcoming Presidential election, while for Mr Xi, it's a waiting game, Mr Gold said.
"He wants to see Donald Trump fail and he's willing to dig in his heels to make it happen."