London Daily

Focus on the big picture.
Sunday, Oct 05, 2025

Hepatitis in children mystery still being investigated as cases rise

Hepatitis in children mystery still being investigated as cases rise

UK health officials say they are still no clearer on the cause of a rise in liver inflammation, or hepatitis, in children.
A common adenovirus is thought to play a role, but other possibilities are still being investigated.

In the UK, 163 cases have now been identified, and 11 children have received liver transplants.

Cases have been detected in 20 countries worldwide, with nearly 300 children affected, and one death.

"It's important that parents know the likelihood of their child developing hepatitis is extremely low," said Dr Meera Chand, from the UK Health Security Agency (UKHSA).

She said parents should still be alert to the signs - particularly jaundice, a yellow tinge in the whites of the eyes - and they should contact a doctor if concerned.

Since last week, another 18 children in the UK with hepatitis have been identified - 118 live in England, 22 in Scotland, 13 in Wales and 10 in Northern Ireland.

The children's most common symptoms were jaundice and vomiting - and most have been under five years old.

The UKHSA's latest report on cases says there is "some apparent reduction in confirmed cases in the past two weeks overall in the UK".

What's puzzling scientists is that the most likely cause - adenovirus - doesn't normally make children seriously unwell. Passed from person to person via coughs and sneezes, it can cause colds, vomiting and diarrhoea.

However, it's very unusual for adenovirus to be a cause of severe hepatitis in otherwise healthy children, but it has been circulating at high levels since the start of the year after virtually disappearing during the pandemic.

Genetic analysis of samples from some children has found a type of virus called AAV-2 - but it doesn't typically cause illness either, the report says.

Scientists are also keeping a close eye on another type of adenovirus, called F41.

"Our investigations continue to suggest that there is an association with adenovirus, and our studies are now testing this association rigorously," Dr Chand said.

"We are also investigating other contributors."

These include whether a new variant of adenovirus has developed which is making children more ill, or whether a previous infection, such as Covid, could be a factor.

Another possibility is that the pandemic, by delaying young children's exposure to a number of different viruses because of reduced social mixing, may have made them more prone to becoming ill.

And health officials are also exploring whether there could be a link with dogs. A number of families affected said they owned dogs or had come into contact with them, but UKHSA also acknowledges that having a pet dog is common in the UK.

The UKHSA says there is no evidence of any link to the Covid-19 vaccine, because most children with hepatitis were too young to receive it.
Newsletter

Related Articles

0:00
0:00
Close
Trump Stands Firm in Shutdown Showdown and Declares War on Drug Cartels — Turning Crisis into Opportunity
Surge of U.S. Billionaires Transforms London’s Peninsula Apartments into Ultra-Luxury Stronghold
Pro Europe and Anti-War Babiš Poised to Return to Power After Czech Parliamentary Vote
Jeff Bezos Calls AI Surge a ‘Good’ Bubble, Urges Focus on Lasting Innovation
Japan’s Ruling Party Chooses Sanae Takaichi, Clearing Path to First Female Prime Minister
Sean ‘Diddy’ Combs Sentenced to Fifty Months in Prison Following Prostitution Conviction
Taylor Swift’s ‘Showgirl’ Launch Extends Billion-Dollar Empire
Trump Administration Launches “TrumpRx” Plan to Enable Direct Drug Sales at Deep Discounts
Trump Announces Intention to Impose 100 Percent Tariff on Foreign-Made Films
Altman Says GPT-5 Already Outpaces Him, Warns AI Could Automate 40% of Work
Singapore and Hong Kong Vie to Dominate Asia’s Rising Gold Trade
Trump Organization Teams with Saudi Developer on $1 Billion Trump Plaza in Jeddah
Manhattan Sees Surge in Office-to-Housing Conversions, Highest Since 2008
Switzerland and U.S. Issue Joint Assurance Against Currency Manipulation
Electronic Arts to Be Taken Private in Historic $55 Billion Buyout
Thomas Jacob Sanford Named as Suspect in Deadly Michigan Church Shooting and Arson
Russian Research Vessel 'Yantar' Tracked Mapping Europe’s Subsea Cables, Raising Security Alarms
New York Man Arrested After On-Air Confession to 2017 Parents’ Murders
U.S. Defense Chief Orders Sudden Summit of Hundreds of Generals and Admirals
Global Cruise Industry Posts Dramatic Comeback with 34.6 Million Passengers in 2024
Trump Claims FBI Planted 274 Agents at Capitol Riot, Citing Unverified Reports
India: Internet Suspended in Bareilly Amid Communal Clashes Between Muslims and Hindus
Supreme Court Extends Freeze on Nearly $5 Billion in U.S. Foreign Aid at Trump’s Request
Archaeologists Recover Statues and Temples from 2,000-Year-Old Sunken City off Alexandria
China Deploys 2,000 Workers to Spain to Build Major EV Battery Factory, Raising European Dependence
Speed Takes Over: How Drive-Through Coffee Chains Are Rewriting U.S. Coffee Culture
U.S. Demands Brussels Scrutinize Digital Rules to Prevent Bias Against American Tech
Ringo Starr Champions Enduring Beatles Legacy While Debuting Las Vegas Art Show
Private Equity’s Fundraising Surge Triggers Concern of European Market Shake-Out
Colombian President Petro Vows to Mobilize Volunteers for Gaza and Joins List of Fighters
FBI Removes Agents Who Kneeled at 2020 Protest, Citing Breach of Professional Conduct
Trump Alleges ‘Triple Sabotage’ at United Nations After Escalator and Teleprompter Failures
Shock in France: 5 Years in Prison for Former President Nicolas Sarkozy
Tokyo’s Jimbōchō Named World’s Coolest Neighbourhood for 2025
European Officials Fear Trump May Shift Blame for Ukraine War onto EU
BNP Paribas Abandons Ban on 'Controversial Weapons' Financing Amid Europe’s Defence Push
Typhoon Ragasa Leaves Trail of Destruction Across East Asia Before Making Landfall in China
The Personality Rights Challenge in India’s AI Era
Big Banks Rebuild in Hong Kong as Deal Volume Surges
Italy Considers Freezing Retirement Age at 67 to Avert Scheduled Hike
Italian City to Impose Tax on Visiting Dogs Starting in 2026
Arnault Denounces Proposed Wealth Tax as Threat to French Economy
Study Finds No Safe Level of Alcohol for Dementia Risk
Denmark Investigates Drone Incursion, Does Not Rule Out Russian Involvement
Lilly CEO Warns UK Is ‘Worst Country in Europe’ for Drug Prices, Pulls Back Investment
Nigel Farage Emerges as Central Force in British Politics with Reform UK Surge
Disney Reinstates ‘Jimmy Kimmel Live!’ after Six-Day Suspension over Charlie Kirk Comments
U.S. Prosecutors Move to Break Up Google’s Advertising Monopoly
Nvidia Pledges Up to $100 Billion Investment in OpenAI to Power Massive AI Data Center Build-Out
U.S. Signals ‘Large and Forceful’ Support for Argentina Amid Market Turmoil
×