London Daily

Focus on the big picture.

What we know -- and what we don't -- about the UK coronavirus variant

What we know -- and what we don't -- about the UK coronavirus variant

The United Kingdom has identified a new, more contagious coronavirus variant linked to a recent surge in cases in England.

The new mutation is being called VUI-202012/01 -- the first "Variant Under Investigation" in the UK in December 2020. While scientists hunt for more information about the variant, its impact is already being felt, with dozens of countries imposing restrictions on travelers from the UK.

Here's what you need to know.

What is a variant and why are officials concerned about this one?


A variant occurs when the genetic structure of a virus changes. All viruses mutate over time and new variants are common, including for the novel coronavirus.

Like other variants, this one carries a genetic fingerprint that makes it easy to track, and it happens to be one that is now widespread in southeast England.

That alone does not necessarily mean a variant is more contagious or dangerous.

But scientists advising the UK government have estimated that this variant could be up to 70% more effective at spreading than others. Peter Horby, chair of the New and Emerging Respiratory Virus Threats Advisory Group (NERVTAG), said Wednesday that scientists were "confident" the new variant is "spreading faster than other virus variants."

Speaking at an emergency meeting of the UK Parliament Science and Technology Committee, Horby explained that the new variant has "some kind of biological advantage to make it spread faster."

Scientists still don't have a complete picture as to why, he said, but that there were a few different scenarios they were investigating.

There is preliminary evidence to suggest that the new strain results in a person holding a higher viral load, which means the virus is easier to pass on, Horby said.

Another possibility is that people are becoming infected more quickly after exposure, he said. It's also possible, he added, that people are infectious for longer.

All of these potential explanations, however, lead to the same conclusion: The virus is spreading faster.

England's chief medical officer, Chris Whitty, has said the variant contains 23 changes, including 17 key "non-synonymous" mutations.

"These are ones that change the protein sequence of one of the viral genes," said Jeffrey Barrett, lead Covid-19 statistical geneticist at the UK's Wellcome Sanger Institute, according to the Science Media Centre.

The World Health Organization said Tuesday that these mutations "may influence the transmissibility of the virus in humans," though it added that further laboratory investigations were needed.

Scientist Neil Ferguson, a member of NERVTAG, said Monday that the variant may be more infectious for children. "There is a hint is that [the variant] ... has a higher propensity to infect children," he told a press briefing organized by the Science Media Centre (SMC), though he cautioned that more data was needed.

Severe illness due to Covid-19 is still relatively rare for children.

The findings have immediate implications for virus control. More cases could place an even greater strain on hospitals and health care staff just as they enter an already particularly difficult winter period, and ultimately lead to more deaths.

Where did the variant originate and how has it taken hold?


The new variant is believed to have originated in southeast England, according to the WHO. Public Health England (PHE) says backwards tracing, using genetic evidence, suggests the variant first emerged in England in September. It then circulated in very low levels until mid-November.

"The increase in cases linked to the new variant first came to light in late November when PHE was investigating why infection rates in Kent [in southeast
England] were not falling despite national restrictions. We then discovered a cluster linked to this variant spreading rapidly into London and Essex," PHE said.

But Sharon Peacock, professor of public health and microbiology at the University of Cambridge, said scientists did not know whether the mutation had originated in southeast England or whether it was introduced there from elsewhere.

Speaking at a press briefing on Tuesday, Peacock also praised the strength of the UK's genetic surveillance operation. "If you're going to find [a variant] anywhere, you're going to find it probably here first," she said. "And if this occurs in places that don't have any sequencing, you're not going to find it at all unless you're using [other methods.]"

Whitty said Saturday the variant was responsible for 60% of new infections in London, which have nearly doubled in the last week alone. On Wednesday,
Northern Ireland's Health Minister Robin Swann said the variant was detected in its borders.

The region's health authorities said it was "increasingly likely" that the new variant has established itself across the UK."I would advise the public to act on the assumption that it is already well established in Northern Ireland and that the person they pass in the street or stand next to in a queue may have it," the region's Chief Medical Officer Dr. Michael McBride said in a statement.

Some experts have suggested that this new variant could have been amplified because of a superspreader event, meaning the current spike in cases could also have been caused by human behavior.

"When we first started to see this enormous rise, it could have been a number of things. It could have been [due to] changes in behavior," said Judith Breuer, professor of virology at UCL, during a briefing on Tuesday.

"[But now] it is very clear that there is a significant rise in the prevalence of this variant and that this is likely to be due to biological features of the variant and indeed increased transmissability."

Which countries are affected?


The variant has already spread globally. As well as the UK, the variant has also been detected in Denmark, Belgium, the Netherlands and Australia, according to the WHO.

Australia has identified two cases of the variant in a quarantined area in Sydney and Italy has also identified one patient infected with the variant.

A similar but separate variant has also been identified in South Africa, where scientists say it is spreading quickly along coastal areas of the country.

On Wednesday, British health authorities said that two cases of the South African variant had been detected in the UK. Public Health England Managing

Director Susan Hopkins said that the Covid-19 variants discovered in the UK and in South Africa are both "more transmissible."

Is the new variant more deadly?


There is no evidence as of now to suggest that the new variant is more deadly, according to Whitty and the WHO, though it is too early to tell.

Several experts have noted that in some cases, virus mutations that increase transmissibility are accompanied by a drop in virulence and mortality rates.

"As viruses are transmitted, those that allow for increased virological 'success' can be selected for, which changes the properties of the virus over time. This typically leads to more transmission and less virulence," Martin Hibberd, professor of emerging infectious disease at the London School of Hygiene &

Tropical Medicine, told the SMC.

Will the developed vaccines work against this variant?


There are no signs yet that the current vaccine frontrunners won't work against this new variant, experts and drugmakers have said.

The companies behind the first two vaccines to gain authorization in the US -- Pfizer/BioNTech and Moderna -- are testing their shots to double-check that they're effective against the variant.

The coronavirus has mutated before, and both firms say their vaccines worked against other variations of the virus.

BioNTech's CEO Ugur Sahin said he has "scientific confidence" that the current Pfizer-BioNTech vaccine could work against the new variant, but full data will be available in two weeks.

Some US-based scientists have said that it's possible this new variant might, to a small extent, undermine the vaccines.

Trevor Bedford, an associate professor in the vaccine and infectious disease division of the Fred Hutchinson Cancer Research Center, said: "You could imagine some modest hit to vaccine efficacy, which wouldn't be good, but I don't think it will break the vaccine."

Bedford explained that the variant could possibly lower the Pfizer/BioNTech vaccine's effectiveness from 95%, which would be a "a modest effect -- not a dramatic effect."

BioNTech's Sahin said the new variant may however require countries to vaccinate more of the population, raising the bar for achieving herd immunity.

"[On] the topic of herd immunity there is always the discussion about 60-70%," he told a news conference Tuesday. "But if the virus becomes more efficient in infecting people, we might need even a high vaccination rate to ensure that normal life can continue without interruption."

What measures are being taken to contain the variant?


Large swathes of England, including London and the southeast, are now under strict Tier 4 Covid-19 restrictions, and UK government health experts have suggested additional restrictions could be required to beat back this variant.

Dozens of countries across Europe, the Middle East and the Americas have also announced travel bans for the UK, or new testing and quarantine requirements for UK arrivals.

The White House is considering requiring travelers from the UK to present proof of a negative test before arriving in the US, two administration officials have told CNN.

In the UK, new measures were announced to combat the potential spread of the South African variant on Wednesday, with travelers arriving into the UK from South Africa now having to quarantine for 15 days upon arrival. People in the UK who have been in contact with people arriving from South Africa in the past 15 days have also been instructed to go into quarantine immediately.

In its press release on Tuesday, the WHO issued a reminder of the basic measures to reduce the transmission of the virus: avoid close contact with people who are infected, wash your hands frequently, and wear a mask.

Newsletter

Related Articles

London Daily
0:00
0:00
Close
Unelected PM of the UK holds an emergency meeting because a candidate got voted in… which he says is a threat to democracy…
You Are So Beautiful
Rob Schneider explains California reparations legislation.
Postmodern Jukebox European Tour Version
Who knew badminton could get so intense?
An old French tune (by Georges Brassens) Pomplamoose ft. John Schroeder
Farmers break through police barriers in Brussels.
Sattahip Motor Show 20
London's Iconic British Telecom Tower Sold To Become Hotel
SONATE AU CLAIR DE LUNE - Moonlight sonata
Ukraine Arrests Father-Son Duo In Lockbit Cybercrime Bust
A kiss to build a dream on
US Offers $15 Million For Info On Leaders Of Cybercrime Group Lockbit
Wonderful Tonight - Eric Clapton (Boyce Avenue acoustic cover)
Russia Claims UK Cultural Agency Spied for Ukraine
Mean Blues
Apple warns against drying iPhones with rice
La Chansonnette
Alexei Navalny: UK sanctions Russian prison chiefs after activist's death
Pattaya Addicts
German economy is in 'troubled waters' - ministry
Franz Liszt - Liebestraum - Love Dream
In a recent High Court hearing, the U.S. argued that Julian Assange endangered lives by releasing classified information.
Dream a little dream of me
New video
Unchained Melody sung like you've NEVER heard!
Tucker Carlson says Boris Johnson wants "a million dollars, in Bitcoin or cash, from Tucker Carlson to talk about Ukraine.
Dave Brubeck - Take Five
Russia is rebuilding capacity to destabilize European countries, new UK report warns
Édith Piaf - Non, Je Ne Regrette Rien (Sofie)
EU Commission wants anti-drone defenses at Brussels HQ
Rondo Alla Turca
Von der Leyen’s 2nd-term pitch: More military might, less climate talk
Kiss of fire
Global Law Enforcement Dismantles Lockbit Ransomware Operation
Tom Jones - I´ll Never Fall In Love Again 1967, 1989, 2001
Prince William Urges End to Gaza Conflict
Israel Cachao López - Guajira Clásica
UK court to hear Assange's final appeal against extradition to the US, where he faces charges related to his journalistic work—the publication of a classified video in 2010 that exposed US war crimes against humanity.
Edward Maya - Stereo Love (feat. Vika Jigulina) (Extended Mix)
About 50-60% kids either chose to be YouTuber or influencer
Strauss - Radetzky March - Karajan
A viral video of Nationals MP Barnaby Joyce lying on a Canberra footpath is celebrated by his media mates.
La vie en rose
European Countries React to Navalny's Death by Summoning Russian Diplomats
The Temptations - My Girl (Smokey Robinson Tribute) 2006 Kennedy Cent
Israel has gone ‘beyond self-defence’ in Gaza, says Labour’s Streeting
Orlando Cachaito Lopez Redencion
English farmers to be offered ‘largest ever’ grant scheme amid food security concerns
Edith Piaf - NON, JE NE REGRETTE RIEN
Cameron government knew Post Office ditched Horizon IT investigation
RADETZKY MARCH-2008-Wien, New Year Concert
EU Calls for Immediate Ceasefire in Gaza Conflict
Only you (And you alone)
EU Vows To Hold Putin "Accountable" After Meeting Alexei Navalny's Wife
Strangers In The Night
EU Launches Probe Into TikTok Over Child Protection Under Digital Content Law
Charles Aznavour - La Boheme
The EU Initiates Naval Mission to Defend Red Sea Trade Routes
Summer time
EU and UK Announce Joint Effort on Migration
Sting and Stevie Wonder - Fragile (from Sting's 60th birthday concert)
Brazil's Lula Likens Gaza Operation to Holocaust, Israel Says "Red Line" Crossed
Aux Champs Elysees
Ministers Confirm Proposal to Prohibit Mobile Phone Usage in English Schools
Stand By Me - Ben E. King (Boyce Avenue acoustic cover)
Microsoft-backed OpenAI valued at $80bn after company completes deal
La Mer (Beyond the Sea) – Avalon Jazz Band
‘Alexei would want to tell Russia not to give up fighting’
She
Rwandan Footballer's Dismissal Sparks Concerns Over UK Asylum Plan
Nathalie Song by Enzo Petrachi Stjepan Hauser Cello
Whisky Challenges China's Baijiu Market During New Year Celebrations
Shape of My Heart - Sting (Boyce Avenue acoustic cover)
Avdiivka - Symbol Of Ukrainian Resistance Now In Control Of Russian Troops
Radiohead - Creep
Putin Critic Alexei Navalny's "Killers" Refusing To Hand Over Body, Say Allies
Quizás,Quizás,Quizás - Andrea Bocelli - Jennifer Lopez
"Historic Step": Zelensky Signs Security Pact With Germany
Perhaps, Perhaps, Perhaps - Multi-Couples
"Historic Step": Zelensky Signs Security Pact With Germany
Pentatonix Havana
20 Tech Giants Sign Effort To Fight AI Election Interference Across Globe
Paula Cole - Autumn Leaves
Joe Biden Accuses Putin of Causing Navalny's Death
Oscar Benton Bensonhurst Blues
Russian opposition leader Alexey Navalny has died at the Arctic prison colony
OH NANANA vs ABUSADAMENTE
Tucker Carlson grocery shopping in Russia. This is so interesting.
Nina Simone - ”I Put A Spell On You”. Vezi aici cum cântă Jeremy Ragsd
Julian Assange's Wife Warns of His Death if Extradited to US
NIGHTWISH - The Phantom Of The Opera
‘A lot higher than we expected’: Russian arms production worries Europe’s war planners
Motorshow 2016 Tanjay Negros Oriental
Greece Legalizes Same-Sex Marriage and Adoption Rights
Monica Bellucci - Ti Amo
Hungarian Foreign Minister: Europeans will lose Europe, the Union's policy must change drastically
Michael Jackson - Billie Jean Milena The Voice France 2018
In Britain Homeowners are receiving CPO’s (Compulsory Purchase Orders) so their homes can be redistributed to migrants
Michael Buble (Help Me Make It Through The Night) feat Loren Allred
Memories Canon In D - Maroon 5 (Boyce Avenue piano acoustic cover)
Matteo Simoni - Marina
Maroon 5 - One More Night
Maroon 5 - Memories
Mark Knopfler - Brothers In Arms (Berlin 2007 Live)
Mark Knopfler & Emmylou Harris - Romeo And Juliet (Real Live Roadrunni
Marina, Marina - The LUCKY DUCKIES intimist live concert at Guimarães
Major Lazer & DJ Snake – Lean On Mauranne The Voice France 2016
Love Theme from Romeo and Juliet - Joslin - Henri Mancini, Nino Rota
LoLa & Hauser - Love Story
Linkin Park Jay-Z - Numb Encore (Live 8 2005)
Hallelujah Mennel Ibtissem, The Voice France Leonard Cohen
Leonard Cohen - Dance Me to the End of Love
Leonard Cohen & Natasha Rostova - Dance me to the end of love
La casa de papel - Bella Ciao
La Camisa Negra
L'italiano (Toto Cutugno) - The Gypsy Queens
Juanes - La Camisa Negra
Jonathan and Charlotte - Britain's Got Talent 2012 Live Semi Final - U
John Powell - Assassin's Tango
Joe Cocker - You Can Leave Your Hat On (LIVE in Dortmund)
Joe Cocker - Unchain My Heart 2002 Live
Joe Cocker - A Whiter Shade Of Pale
Jay Z & Alicia Keys - Empire State of Mind LIVE
Jason Mraz - Im Yours (live)
Jarrod Radnich - Bohemian Rhapsody - Virtuosic Piano Solo
James Blunt - You're Beautiful
James Blunt - You're Beautiful & Bonfire Heart (Live at The Nobel Peac)
If You Go Away - Helen Merrill & Stan Getz (Tribute to Virna Lisi)
I'LL BE MISSING YOU
I Say a Little Prayer
Hotel California ( Eagles ) 1994 Live
Historia de un amor - Luz Casal. Vezi interpretarea Biancăi Sumanariu
Here Comes The Sun - The Beatles (Boyce Avenue acoustic cover) on Spot
Heart - Stairway to Heaven Led Zeppelin - Kennedy Center Honors
HAVANA by Camila Cabello Zumba Pre Cooldown TML Crew Kramer Pastra
HAUSER and Señorita - I Will Always Love You
HAUSER - Waka Waka
HAUSER - Sway
HAUSER - Lambada
HAUSER - Historia de un Amor
HAUSER - Despacito
Great Pretender
Georgia May Foote & Giovanni Pernice Samba to 'Volare' - Strictly Come
Gary Moore - Still Got The Blues
GIPSY KINGS VOLARE Penelope Cruz
Fugees - Killing Me Softly With His Song
French Latino - Historia de un Amor
For A Few Dollars More The Danish National Symphony Orchestra (Live)
Flashdance • What a Feeling • Irene Cara
Filip Rudan - “Someone You Loved” Audicija 4 The Voice Hrvatska Sez
Eric Clapton - Wonderful Tonight
Enya - Only Time
Enrique Iglesias - Bailando (English Version) ft. Sean Paul
Enrique Iglesias - Bailamos
Elena Yerevan Historia de un amor
Ed Sheeran - Shape of You (Official Music Video)
Ed Sheeran - Perfect Symphony [with Andrea Bocelli]
Ed Sheeran - Perfect (Official Music Video)
Easy On Me - Adele (Boyce Avenue 90’s style piano acoustic cover) on S
ERA - Ameno
ELENA YEREVAN- Cancion Del Mariachi-IN STUDIO-2017 DPR
Dust In The Wind - Kansas (Boyce Avenue acoustic cover)
Don't Let Me Be Misunderstood
Despacito x Shape Of You - Pentatonix
Deep Purple - Child In Time - Live (1970)
David Foster When A Man Loves A WomanIt's A Mans World (SealMichael Bo
Dance me to the end of Love ( Pi-Air Design )
Coolio - Gangsta's Paradise (feat. L.V.) [Official Music Video]
Conquest Of Paradise (Vangelis), played on Böhm Emporio organ
Cielito Lindo
Chico & The Gypsies - Bamboleo
Canción Del Mariachi - Antonio Banderas, Los Lobos • Desperado
Camila Cabello - Havana (Audio) ft. Young Thug
Camila Cabello - Havana ( cover by J.Fla )
California Dreamin' - The Mamas & The Papas José Feliciano (Boyce Ave
Buster Benton - Money Is The Name of The Game
Hallelujah Pentatonix
Bobby McFerrin - Don't Worry Be Happy (Official Music Video)
Bob Dylan - Knockin' On Heaven's Door Emilia The Voice Kids France
Besame Mucho - Cesaria Evora
Ben E. King - Stand by Me Sax Cover Alexandra Ilieva Thomann
Bella Ciao
Bella Ciao - INSTRUMENTAL
Beautiful in White x Canon in D (Piano Cover by Riyandi Kusuma)
Bad Romance - Vintage 1920's Gatsby Style Lady Gaga Cover ft. Ariana Savalas & Sarah Reich(1)
BELLA CIAO 2020 - KARAOKE ITALIANO
BAMBOLEO - Gipsy Kings • Antonio Banderas, Katya Virshilas
BAILANDO (original)
Awesome Ukrainian yodeler - SOFIA SHKIDCHENKO (with English subtitles)
Avicii - The Nights
Atom - The Great Gig in the Sky
Aretha Franklin - (You Make Me Feel Like) A Natural Woman (Official Ly
Antonio Banderas - Cancion del Mariachi (Desperado)
André Rieu - Zorba's Dance (Sirtaki)
André Rieu - Can't Help Falling In Love
André Rieu & Mirusia - Ave Maria
Andrew Reyes Elton John - Don't Let The Sun Go Down The Voice 2020 (
Andreas Kümmert Whiter Shade Of Pale The Voice of Germany 2013 Showd
And I Love You So
All About That Bass - Postmodern Jukebox European Tour Version
Alan Walker - Faded (Piano Cover)
Ain't No Sunshine -- Bill Withers (cover by Canen 12 y.o.)
African music
Adriana Vidović - “Creep” Audicija 4 The Voice Hrvatska Sezona 3
Adriana Vidović - “Believer” Nokaut 3 The Voice Hrvatska Sezona 3
A Fistful of Dollars - The Danish National Symphony Orchestra and Tuva
4 Beautiful Soundtracks Relaxing Piano [10min]
2CELLOS - Whole Lotta Love vs. Beethoven 5th Symphony [OFFICIAL VIDEO]
2CELLOS - Smooth Criminal (Live at Suntory Hall, Tokyo)
2CELLOS - Smells Like Teen Spirit [Live at Sydney Opera House]
2CELLOS - Despacito [OFFICIAL VIDEO]
13 Year Old Girl Playing Il Silenzio (The Silence) - André Rieu
094.All About That Bass
00 - SADNESS PART 1
(Ghost) Riders In the Sky (American Outlaws Live at Nassau Coliseum, 1
(Everything I Do) I Do It For You - Bryan Adams (Boyce Avenue ft. Conn
What a wonderful world
Moon river
×