Researchers at the University of Oxford say Covid-19 leads to a risk of rare blood clots that's several-times higher than that of current vaccines, amid concerns that the jabs may be to blame for the potentially deadly condition.
The report released on Thursday says the risk of the rare condition known as cerebral venous thrombosis (CVT) following
Covid-19 infection is “around 100 times greater than normal” and “several times higher” than it is post-vaccination or after flu.
Researchers looked at health records of 500,000
Covid-19 patients to estimate the absolute incidence of CVT in the two weeks following
Covid-19 diagnosis, flu, or vaccination against
coronavirus. They found that clotting is around eight times more likely to occur after contracting
Covid-19 than after immunization with the AZ-Oxford
Covid-19
vaccine. Compared to the
vaccines made by
Pfizer or Moderna, the risk of a CVT from
Covid-19 is about 10 times greater.
The researchers, however, call for a cautious interpretation of the comparisons since data is still coming in.
“There are concerns about possible associations between
vaccines, and CVT, causing governments and regulators to restrict the use of certain
vaccines. Yet, one key question remained unknown: ‘What is the risk of CVT following a diagnosis of
Covid-19?’” says Professor of Psychiatry and Head of the Translational Neurobiology Group at the University of Oxford Paul Harrison.
Some countries have restricted the use of the Oxford-
AstraZeneca vaccine – which was renamed Vaxzevria – to certain age groups after the European Medicines Agency confirmed the
vaccine’s possible links to cases of blood clotting, several of which were fatal. Denmark halted the use of the jab altogether.
Meanwhile, another EMA-approved
vaccine,
Johnson &
Johnson's, is being investigated in the US and Europe following cases of blood clotting and at least one death.
Both
vaccines are based on a similar method, known as adenoviral vectors. Regulators and researchers are working to find out whether the incidences of blood clotting are caused by an immune response to the adenovirus
vaccines