London Daily

Focus on the big picture.
Wednesday, Dec 17, 2025

Huge plan to map the DNA of all life in British Isles

Huge plan to map the DNA of all life in British Isles

Scientists are planning to sequence the genomes of all species, including plants, animals, fungi, found in Britain and Ireland.

Seventy thousand species.

That’s the best guess for the tally of life, including plants, animals and fungi, found in Britain and Ireland.

And it’s the target of one of biology's most ambitious projects - scientists want to map the DNA of every single one of these organisms.

Having these genomes - each a complete set of genetic information for a species - could transform how we understand the natural world. And there could be benefits for us too in the hunt for nature-inspired medicines and materials.

In Plymouth, the starting point for this immense task is some thick, sticky mud.

Sediment scooped up from the bottom of the Plymouth Sound has been hoisted onto the deck of the research vessel that belongs to the Marine Biological Association.

It's placed in a sieve and hosed off, revealing a host of wriggling creatures.

The sediment in Plymouth is jam packed with life


"You can see we've got some bivalves, which are related to clams and mussels. We've also got a gastropod shell - these are quite similar to terrestrial garden snails. And we've got some brittle stars. So lots of different taxa (groups of organisms), lots of different types of animals, which is great," explains marine biologist Patrick Adkins.

Today he's focussing on marine worms known as polychaetes, and there are lots living in the sediment.

Some look like earthworms and others are covered in tiny bristles, squiggling about. But the weirdest is the mud owl. If you squint, its markings look a bit like the face of an owl, until it extends a tubular proboscis, shattering the illusion.

All of them will have their genomes sequenced for the project, which is called the Darwin Tree of Life and includes participation from the Natural History Museum.

"Even if you look at polychaetes, which is just one group of worms, it's a big task with hundreds and hundreds of species," Patrick says.

"We've now got over 100 species of polychaetes collected - it seems like a lot, but really, it's just the beginning."

These marine worms are known as mud owls


The research covers every kind of habitat.

In Oxfordshire, woodlands are the focus.

As dusk falls, a family of badgers emerge from their sett. They snuffle around in the gloom, hunting for some snacks after their sleep.

The animals here in Wytham Woods have been studied in detail for more than 30 years, but now their genome has just been sequenced too.

The genome of the European badger has now been sequenced as part of the project


"The genome can answer so many questions that we couldn't answer before," says Ming-Shan Tsai from the University of Oxford.

"We can explore why the badger is very different from other animals - and their unique behaviour."

This includes the puzzle of delayed implantation, where badgers mate and an egg is fertilised, but the process of pregnancy is put on hold until it's the best time of year to have a cub.

"Getting a genome will also help us to understand why badgers are more susceptible to tuberculosis, for example, than other animals," she added.

At the centre of this project is the Wellcome Sanger Institute in Cambridge.

Every day, samples from all over the British Isles are arriving.

Whether it's a leaf from a tree, or some blood taken from an animal, the material is weighed, then frozen with liquid nitrogen, and finally pulverised into a fine powder. From this, the DNA can be extracted, and the genome sequenced.

The samples are sent to the Wellcome Sanger Institute


Sanger played a leading role in the human genome project, which took years to complete. Now sequencing a species takes a few days.

Mark Blaxter, who leads the Tree of Life project, says: "When the human genome was sequenced, it changed the way we do human biology forever. And it's really transformed how we see ourselves and how we work with our health and illness.

"And we want to make that possible for all of biology. So we want everybody, working on any species, or any group of species, anywhere in the world, able to have this ultimate foundation."

The genetic work should show how species relate to each other, and reveal their similarities and also where their differences lie.

"It's filling up the library of life," Mark explains.

This single-celled organism was found in some pond water


But the tiniest life forms are posing the biggest challenges.

Jamie McGowan, from the Earlham Institute in Norwich, is staring through a microscope at a single drop of pond water. It’s full of single-celled organisms known as protists.

"There's two little green cells here - they're both micro algae. They're photosynthetic, just like plants," he says.

They are the smallest organisms being sequenced for the project, but it's not easy.

"They're really hard to identify, because some of them look really similar. And they're hard to sequence too because they're starting off with really, really tiny amounts of DNA."

Life on Earth began with single-celled organisms, and we could not exist without them.

"We completely depend on them to survive," Jamie explains.

"Protists occupy a really important position in the food chain, where they eat organisms that are smaller than them, such as bacteria and viruses. And then they, in turn, get eaten by larger organisms.

"And quite a lot of protists can produce oxygen - in fact they actually produce about half of the planet's oxygen supply.

"So having their genome sequenced is really important to be able to identify them. Their biodiversity is so poorly understood. And we need to protect them, because they're so critical for all of the rest of life."

Rock pools hold many different species which could help to inspire nature-based medicines or materials


Back in Plymouth, and the marine biologists have moved onshore to take a look inside some rock pools.

Each is a colourful microcosmos, containing a multitude of species.

Something flashes past the seaweed.

"It’s a pipefish," says Kes Scott-Somme, a research assistant on the Darwin Tree of Life project. "It's basically like a stretched-out seahorse. They're beautiful - and they're very, very well adapted to their environment. They can live quite high on the shore like this."

But learning about the DNA of creatures like this won't just help us to better understand the species - it could also help us.

"Marine environments are incredibly volatile, and so the animals that live here have to be even more adapted to their space than we are. And that means that they have very specific ways of coping with their environment," says Kes.

"This could help us to find things like antibiotics, medicines and materials. The marine environment is a great place to look for that information."

The Darwin Tree of Life project has a tough deadline - all 70,000 species sequenced by the end of 2030.

There is a lot of work to do, but this project could give us our most detailed understanding yet of the diversity of life.

Newsletter

Related Articles

0:00
0:00
Close
Trump Files $10 Billion Defamation Lawsuit Against BBC as Broadcaster Pledges Legal Defence
UK Says U.S. Tech Deal Talks Still Active Despite Washington’s Suspension of Prosperity Pact
UK Mortgage Rules to Give Greater Flexibility to Borrowers With Irregular Incomes
UK Treasury Moves to Position Britain as Leading Global Hub for Crypto Firms
U.S. Freezes £31 Billion Tech Prosperity Deal With Britain Amid Trade Dispute
Prince Harry and Meghan’s Potential UK Return Gains New Momentum Amid Security Review and Royal Dialogue
Zelensky Opens High-Stakes Peace Talks in Berlin with Trump Envoy and European Leaders
Historical Reflections on Press Freedom Emerge Amid Debate Over Trump’s Media Policies
UK Boosts Protection for Jewish Communities After Sydney Hanukkah Attack
UK Government Declines to Comment After ICC Prosecutor Alleges Britain Threatened to Defund Court Over Israel Arrest Warrant
Apple Shutters All Retail Stores in the United Kingdom Under New National COVID-19 Lockdown
US–UK Technology Partnership Strains as Key Trade Disagreements Emerge
UK Police Confirm No Further Action Over Allegation That Andrew Asked Bodyguard to Investigate Virginia Giuffre
Giuffre Family Expresses Deep Disappointment as UK Police Decline New Inquiry Into Andrew Mountbatten-Windsor Claims
Transatlantic Trade Ambitions Hit a Snag as UK–US Deal Faces Emerging Challenges
Ex-ICC Prosecutor Alleges UK Threatened to Withdraw Funding Over Netanyahu Arrest Warrant Bid
UK Disciplinary Tribunal Clears Carter-Ruck Lawyer of Misconduct in OneCoin Case
‘Pink Ladies’ Emerge as Prominent Face of UK Anti-Immigration Protests
Nigel Farage Says Reform UK Has Become Britain’s Largest Party as Labour Membership Falls Sharply
Google DeepMind and UK Government Launch First Automated AI Lab to Accelerate Scientific Discovery
UK Economy Falters Ahead of Budget as Growth Contracts and Confidence Wanes
Australia Approves Increased Foreign Stake in Strategic Defence Shipbuilder
Former UK Prime Minister Boris Johnson proclaims, “For Ukraine, surrendering their land would be a nightmare.”
Microsoft Challenges £2.1 Billion UK Cloud Licensing Lawsuit at Competition Tribunal
Fake Doctor in Uttar Pradesh Accused of Killing Woman After Performing YouTube-Based Surgery
Hackers Are Hiding Malware in Open-Source Tools and IDE Extensions
Traveling to USA? Homeland Security moving toward requiring foreign travelers to share social media history
UK Officials Push Back at Trump Saying European Leaders ‘Talk Too Much’ About Ukraine
UK Warns of Escalating Cyber Assault Linked to Putin’s State-Backed Operations
UK Consumer Spending Falters in November as Households Hold Back Ahead of Budget
UK Orders Fresh Review of Prince Harry’s Security Status After Formal Request
U.S. Authorises Nvidia to Sell H200 AI Chips to China Under Security Controls
Trump in Direct Assault: European Leaders Are Weak, Immigration a Disaster. Russia Is Strong and Big — and Will Win
"App recommendation" or disguised advertisement? ChatGPT Premium users are furious
"The Great Filtering": Australia Blocks Hundreds of Thousands of Minors From Social Networks
Mark Zuckerberg Pulls Back From Metaverse After $70 Billion Loss as Meta Shifts Priorities to AI
Nvidia CEO Says U.S. Data-Center Builds Take Years while China ‘Builds a Hospital in a Weekend’
Indian Airports in Turmoil as IndiGo Cancels Over a Thousand Flights, Stranding Thousands
Hollywood Industry on Edge as Netflix Secures Near-$60 Bln Loan for Warner Bros Takeover
Drugs and Assassinations: The Connection Between the Italian Mafia and Football Ultras
Hollywood megadeal: Netflix acquires Warner Bros. Discovery for 83 billion dollars
The Disregard for a Europe ‘in Danger of Erasure,’ the Shift Toward Russia: Trump’s Strategic Policy Document
Two and a Half Weeks After the Major Outage: A Cloudflare Malfunction Brings Down Multiple Sites
UK data-regulator demands urgent clarity on racial bias in police facial-recognition systems
Labour Uses Biscuits to Explain UK Debt — MPs Lean Into Social Media to Reach New Audiences
German President Lays Wreath at Coventry as UK-Germany Reaffirm Unity Against Russia’s Threat
UK Inquiry Finds Putin ‘Morally Responsible’ for 2018 Novichok Death — London Imposes Broad Sanctions on GRU
India backs down on plan to mandate government “Sanchar Saathi” app on all smartphones
King Charles Welcomes German President Steinmeier to UK in First State Visit by Berlin in 27 Years
UK Plans Major Cutback to Jury Trials as Crown Court Backlog Nears 80,000
×