The children were found with fatal injuries at an address on Flax Street after a man in his 40s was stabbed at a car wash nearby.
The woman, 49, known to the children, was first arrested in connection with the stabbing and then on suspicion of murder.
The children were discovered after police were called to the car wash on Campbell Road.
The stabbed man has since been discharged from hospital.
Detectives are appealing for witnesses and anyone with CCTV or dashcam footage from the area to come forward.
The children's family have been informed and are being supported by specially trained officers.
LONDON DAILY ARCHIVE
Two Children Die in Stoke-on-Trent Home, Woman Arrested for Murder
A woman has been arrested on suspicion of murder after two children, a 11-year-old boy and a 7-year-old girl, died at a home in Stoke-on-Trent.
12 June 2023 · 14:13 UTC
