Although the largest party in Northern Ireland, Sinn Féin remains out of power due to the collapse of the Stormont executive, initiated by the DUP's withdrawal over post-Brexit trade rules.
The party's popularity is growing in the Republic of Ireland, where it aims for a government role, gearing up for the next general election and upcoming local and European elections.
Michelle O'Neill, Sinn Féin's vice-president, highlighted the end of unionist dominance in Northern Ireland and the party's recent electoral successes.
Sinn Féin's potential role in the government in Northern Ireland depends on the DUP ending its boycott of the Stormont institutions.
The conference will see delegates voting on 190 motions that will define the party's stance on various domestic and foreign policy issues.