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Wednesday, Jun 18, 2025

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Research Explores Possible Connection Between COVID-19 Vaccines and Post-Vaccination Syndrome

A study conducted by Yale University investigates symptoms that certain individuals claim to experience following vaccination.
A recent investigation has explored the possible connection between COVID-19 vaccinations and a condition referred to as 'post-vaccination syndrome' (PVS), with results indicating that some individuals may endure prolonged symptoms after receiving the vaccine.

Conducted by scholars at Yale University, the research reveals a variety of symptoms reported by participants, such as exercise intolerance, extreme fatigue, numbness, cognitive fog, insomnia, heart palpitations, tinnitus, dizziness, musculoskeletal pain, and alterations in immune function.

These symptoms generally emerge within one to two days after vaccination and may worsen over time, often continuing well beyond the immediate vaccination period.

Since the beginning of the COVID-19 pandemic, many individuals worldwide have reported potential long-term side effects linked to COVID-19 vaccines, even though these vaccines are crucial in preventing severe illness and death caused by the virus.

Research on the long-term effects of vaccination, particularly concerning PVS, has been limited.

Dr. Akiko Iwasaki, an immunologist leading the Yale study, stressed the necessity for further investigation into this condition, pointing out that individuals suffering from PVS frequently feel neglected due to its absence of formal acknowledgment within the medical field.

The study analyzed data from Yale's Listen to Immune, Symptom, and Treatment Experiences Now (LISTEN) Study, which included 42 participants reporting symptoms of PVS and a control group of 22 individuals who did not exhibit related symptoms.

The analysis uncovered variations in the immune profiles of those with PVS compared to the controls, including similarities to findings observed in patients with long COVID.

Significantly, a resurgence of the Epstein-Barr virus was noted among PVS participants; this virus can lie dormant and is linked to several conditions, such as mononucleosis and multiple sclerosis.

The researchers recognized that their findings are preliminary and called for more comprehensive studies to determine the prevalence and underlying mechanisms of PVS.

They expressed optimism that continued research could lead to better diagnostics and treatment options for those experiencing this syndrome.

A deeper understanding could help shape future vaccine designs aimed at minimizing adverse effects, diagnosing PVS, and implementing targeted treatment approaches.
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