At around 04:00 BST, two people were found dead in Ilkeston Road, and a man was found dead in Magdala Road, about a 10-minute drive away.
Later, a van attempted to run over three people in Milton Street, and a 31-year-old man was arrested on suspicion of murder.
The incidents are being linked, and the arrested man remains in police custody.
There is no information yet on whether the incident was terror-related.
Witnesses reported seeing a young man and woman stabbed in Ilkeston Road at about 04:00 BST, and a man and a woman were among the three injured in Milton Street.
The victims' ages and identities have not been released.
LONDON DAILY ARCHIVE
Nottingham City Center Hit by Series of Attacks, 3 Killed and 3 Injured
Nottingham, UK: On Tuesday morning, three people were killed and three others injured in a series of attacks in Nottingham city center.
13 June 2023 · 12:51 UTC
