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First Successful Pig Kidney Transplant: Patient Discharged from Hospital, Marking Historic Organ Transplantation Milestone

A 62-year-old man named Richard "Rick" Slayman from Weymouth, Massachusetts, has been discharged from Massachusetts General Hospital (MGH) after receiving the world's first successful pig kidney transplant.

05 April 2024 · 00:55 UTC

Slayman, who was suffering from end-stage kidney disease, no longer needs dialysis as the transplanted pig kidney is functioning well.

This groundbreaking achievement, which follows previous unsuccessful attempts using pig organs, is considered a historic milestone in organ transplantation by scientists.

MGH, which is Harvard Medical School's largest teaching hospital, shared the news in a press release on Wednesday.

On March 16, 2023, Mr. Slayman received a genetically-edited pig kidney transplant during a four-hour surgery.

The operation was successful, and his new kidney is now functioning properly, allowing him to stop dialysis.

Mr. Slayman expressed his joy at being able to leave the hospital and return home, stating that it was one of the happiest moments of his life.

In 2018, he had undergone a kidney transplant from a deceased human donor, but last year, the transplanted kidney began to deteriorate.

Mr. Slayman saw the possibility of a pig kidney transplant as a way to help himself and provide hope for the thousands of people in need of a transplant to survive.

A hospital in Boston transplanted a genetically modified pig kidney into a patient with kidney failure.

The kidney was modified by eGenesis, a Cambridge-based pharmaceutical company, to remove harmful pig genes and add human genes for better compatibility.

The hospital, which performed the world's first successful human kidney transplant in 1954, also mentioned ongoing research with eGenesis on xenotransplantation over the past five years.

The Food and Drug Administration approved the procedure under compassionate use, which grants access to experimental treatments for patients with life-threatening conditions.

The text celebrates a historic advancement in transplantation technology, which could help address the global organ shortage, particularly benefiting ethnic minority communities.

This technological advancement could lead to health equity and provide kidney transplants to all patients in need, according to Winfred Williams, a doctor at Massachusetts General Hospital.