Reaching the "milestone" of 20 series seemed like the "perfect time to pause for a little while and catch our breath," the presenting duo said.
The series previously took a pause in 2009 - returning four years later.
ITV's Kevin Lygo said the broadcaster understood why the duo have "a desire to take a pause".
"When you think of Saturday night television you think of Saturday Night Takeaway," ITV's director of television said.
The most recent series of that show launched in February, with ITV1's biggest overnight audience of the year, attracting 6.4 million viewers.
Since its launch in 2002 it has received multiple Bafta and National Television Awards (NTA), including presenting accolades for Ant and Dec.
The pair will continue their exclusive working relationship with ITV, as hosts of popular shows including I'm A Celebrity... Get Me Out Of Here!, Britain's Got Talent and Limitless Win.
"We love making Saturday Night Takeaway, but reaching the milestone of 20 series seemed like the perfect time to pause for a little while and catch our breath," Ant said.
Dec added: "We still have a momentous 20th series to look forward to first so we will do our best to go out (for now) with a bang in 2024."